J
Jinsong Han
Researcher at Northern Hospital
Publications - 17
Citations - 358
Jinsong Han is an academic researcher from Northern Hospital. The author has contributed to research in topics: Atrial fibrillation & Reperfusion injury. The author has an hindex of 8, co-authored 15 publications receiving 262 citations.
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Journal ArticleDOI
Melatonin protects diabetic heart against ischemia-reperfusion injury, role of membrane receptor-dependent cGMP-PKG activation
Liming Yu,Wen-cheng Di,Xue Dong,Zhi Li,Yong Zhang,Xiaodong Xue,Yinli Xu,Jian Zhang,Xiong Xiao,Jinsong Han,Yu Liu,Yang Yang,Yang Yang,Huishan Wang +13 more
TL;DR: Melatonin ameliorated diabetic MI/R injury by modulating Nrf-2-HO-1 and MAPK signaling, thus reducing myocardial apoptosis and oxidative stress and preserving cardiac function, and melatonin membrane receptors (especially MT2 receptor)-dependent cGMP-PKGIα signaling played a critical role in this process.
Journal ArticleDOI
Diallyl trisulfide ameliorates myocardial ischemia–reperfusion injury by reducing oxidative stress and endoplasmic reticulum stress-mediated apoptosis in type 1 diabetic rats: role of SIRT1 activation
Liming Yu,Shu Li,Xinlong Tang,Zhi Li,Jian Zhang,Xiaodong Xue,Jinsong Han,Yu Liu,Yuji Zhang,Yong Zhang,Yinli Xu,Yang Yang,Yang Yang,Yang Yang,Huishan Wang +14 more
TL;DR: Perioperative DATS treatment effectively ameliorates MI/R injury in type 1 diabetic setting by enhancing cardiac SIRT1 signaling, thus reducing myocardial apoptosis and eventually preserving cardiac function.
Journal ArticleDOI
Gender differences in fibrosis remodeling in patients with long-standing persistent atrial fibrillation.
Zhi Li,Zeng-wei Wang,Zongtao Yin,Yuji Zhang,Xiaodong Xue,Jinsong Han,Yan Zhu,Jian Zhang,Maximilian Y. Emmert,Huishan Wang +9 more
TL;DR: The data suggest that the aggravation of fibrosis remodeling in women may be an important reason for the low success rate of AF catheter ablation when compared to men, and inhibiting the TGFβ/Smad3 pathway-mediated fibrosis could represent an interesting target for future therapeutic concepts to improve the success rate.
Journal ArticleDOI
Polydatin Protects Diabetic Heart against Ischemia-Reperfusion Injury via Notch1/Hes1-Mediated Activation of Pten/Akt Signaling.
Liming Yu,Zhi Li,Xue Dong,Xiaodong Xue,Yu Liu,Shu Xu,Jian Zhang,Jinsong Han,Yang Yang,Huishan Wang +9 more
TL;DR: Polydatin effectively reduced MI/R injury and improved left ventricular functional recovery under diabetic condition by ameliorating oxidative/nitrative stress damage.
Journal ArticleDOI
Diallyl trisulfide exerts cardioprotection against myocardial ischemia-reperfusion injury in diabetic state, role of AMPK-mediated AKT/GSK-3β/HIF-1α activation
Liming Yu,Wencheng Di,Xue Dong,Zhi Li,Xiaodong Xue,Jian Zhang,Qi Wang,Xiong Xiao,Jinsong Han,Yang Yang,Huishan Wang +10 more
TL;DR: Data showed that DATS protected against MI/R injury in diabetic state by attenuating cellular apoptosis via AMPK-mediated AKT/GSK-3β/HIF-1α signaling and its cardioprotective effect deserves further study.