Jiří Novák

TL;DR: The utility of fingerprinting single chemicals for an improved understanding of the biological effect of pollutants is demonstrated, and the need to apply bioassays for water quality monitoring is highlighted in order to prevent underestimation of the overall biological effect.

TL;DR: An integrated analytical and bioanalytical approach was applied to investigate the impact of untreated wastewater effluents from the city of Novi Sad, Serbia, into the River Danube, demonstrating the enormous dilution capacity of this large river.

TL;DR: The importance of fingerprinting the effects of detected chemicals is highlighted, as they explain less than 0.2% of the biological effect in the PXR activation, adaptive stress response, and fish embryo toxicity assays.

TL;DR: While the wastewater effluents had a significant contribution to micropollutant burden downstream, both chemical analysis and bioanalysis showed a relevant contribution of diffuse sources from upstream during low flow conditions, suggesting that upgrading WWTPs will not completely reduce the micropolutants burden, but further source control measures will be required.

TL;DR: In vivo and in vitro studies on interaction of environmental complex samples, pesticides, poly chlorinated dioxins, polychlorinated biphenyls, polycyclic aromatic compounds and other organic pollutants with physiology of retinoids are summarized.