J
Jirina Bartunkova
Researcher at Charles University in Prague
Publications - 88
Citations - 2050
Jirina Bartunkova is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Immunotherapy & Immune system. The author has an hindex of 18, co-authored 74 publications receiving 1579 citations.
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Journal ArticleDOI
Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response
Jitka Fucikova,Petra Kralikova,Anna Fialová,Tomas Brtnicky,Lukas Rob,Jirina Bartunkova,Radek Spisek +6 more
TL;DR: The data indicate that human prostate cancer, ovarian cancer, and acute lymphoblastic leukemia cells share the key features of immunogenic cell death with mice tumor cells and identify anthracyclines as anticancer drugs capable of inducing immunogeniccell death in sensitive human tumor cells.
Journal ArticleDOI
Defining the critical hurdles in cancer immunotherapy
Bernard A. Fox,Bernard A. Fox,Dolores J. Schendel,Lisa H. Butterfield,Steinar Aamdal,James P. Allison,James P. Allison,Paolo A. Ascierto,Michael B. Atkins,Jirina Bartunkova,Lothar Bergmann,Neil L. Berinstein,Cristina Bonorino,Ernest C. Borden,Jonathan L. Bramson,Cedrik M. Britten,Xuetao Cao,Xuetao Cao,William E. Carson,Alfred E. Chang,Dainius Characiejus,A. Raja Choudhury,George Coukos,Tanja D. de Gruijl,Robert O. Dillman,Harry Dolstra,Glenn Dranoff,Lindy G. Durrant,James H. Finke,Jérôme Galon,Jared Gollob,Cécile Gouttefangeas,Fabio Grizzi,Michele Guida,Leif Håkansson,Kristen Hege,Kristen Hege,Ronald B. Herberman,F. Stephen Hodi,Axel Hoos,Christoph Huber,Patrick Hwu,Kohzoh Imai,Elizabeth M. Jaffee,Sylvia Janetzki,Carl H. June,Pawel Kalinski,Howard L. Kaufman,Koji Kawakami,Yutaka Kawakami,Ulrich Keilholtz,Samir N. Khleif,Rolf Kiessling,Beatrix Kotlan,Guido Kroemer,Réjean Lapointe,Hyam I. Levitsky,Michael T. Lotze,Cristina Maccalli,Michele Maio,Jens Peter Marschner,Michael J. Mastrangelo,Giuseppe Masucci,Ignacio Melero,C. J. M. Melief,William J. Murphy,Brad H. Nelson,Andrea Nicolini,Michael I. Nishimura,Kunle Odunsi,Pamela S. Ohashi,Jill O'Donnell-Tormey,Lloyd J. Old,Christian H. Ottensmeier,Michael Papamichail,Giorgio Parmiani,Graham Pawelec,Enrico Proietti,Shukui Qin,Robert C. Rees,Antoni Ribas,Ruggero Ridolfi,Gerd Ritter,Gerd Ritter,Licia Rivoltini,Pedro Romero,Mohamed L. Salem,Rik J. Scheper,Barbara Seliger,Padmanee Sharma,Hiroshi Shiku,Harpreet Singh-Jasuja,Wenru Song,Per thor Straten,Hideaki Tahara,Zhigang Tian,Zhigang Tian,Sjoerd H. van der Burg,Paul von Hoegen,Ena Wang,Marij J. P. Welters,Hauke Winter,Tara Withington,Jedd D. Wolchok,Weihua Xiao,Laurence Zitvogel,Heinz Zwierzina,Francesco M. Marincola,Thomas F. Gajewski,Jon M. Wigginton,Mary L. Disis +110 more
TL;DR: The critical hurdles identified by representatives of the collaborating organizations, now organized as the World Immunotherapy Council, are presented and discussed in this report.
Journal ArticleDOI
Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors
TL;DR: The distribution of DC subsets in the blood of patients treated with high-dose corticosteroids and the effect of GC on characteristics of DC are investigated to provide further insights into the mechanisms of GC immunosuppressive functions and reveal additional mechanisms of their therapeutic efficiency.
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High hydrostatic pressure induces immunogenic cell death in human tumor cells.
Jitka Fucikova,Irena Moserova,Iva Truxova,Ivana Hermanova,Irena Vancurova,Simona Partlova,Anna Fialová,Ludek Sojka,Pierre-François Cartron,Milan Houska,Lukas Rob,Jirina Bartunkova,Radek Spisek +12 more
TL;DR: HHP acts as a reliable and potent inducer of ICD in human tumor cells and the key features of the endoplasmic reticulum stress‐mediated apoptotic pathway, such as reactive oxygen species production, phosphorylation of the translation initiation factor eIF2α and activation of caspase‐8 were activated by HHP treatment.
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Primary Sjögren syndrome in the paediatric age: a multicentre survey.
Rolando Cimaz,Annachiara Casadei,Carlos D. Rose,Jirina Bartunkova,Anna Sediva,Fernanda Falcini,Paolo Picco,Marco Taglietti,Francesco Zulian,Rebecca ten Cate,Flavio Sztajnbok,Paraskevi V. Voulgari,Alexandros A. Drosos +12 more
TL;DR: Recurrent parotid swelling is a common feature of primary Sjögren syndrome in childhood and often occurs as a presenting feature and Sicca symptoms may be rarer.