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Jirina Bartunkova

Researcher at Charles University in Prague

Publications -  88
Citations -  2050

Jirina Bartunkova is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Immunotherapy & Immune system. The author has an hindex of 18, co-authored 74 publications receiving 1579 citations.

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Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

TL;DR: The data indicate that human prostate cancer, ovarian cancer, and acute lymphoblastic leukemia cells share the key features of immunogenic cell death with mice tumor cells and identify anthracyclines as anticancer drugs capable of inducing immunogeniccell death in sensitive human tumor cells.
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Defining the critical hurdles in cancer immunotherapy

Bernard A. Fox, +110 more
TL;DR: The critical hurdles identified by representatives of the collaborating organizations, now organized as the World Immunotherapy Council, are presented and discussed in this report.
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Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors

TL;DR: The distribution of DC subsets in the blood of patients treated with high-dose corticosteroids and the effect of GC on characteristics of DC are investigated to provide further insights into the mechanisms of GC immunosuppressive functions and reveal additional mechanisms of their therapeutic efficiency.
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High hydrostatic pressure induces immunogenic cell death in human tumor cells.

TL;DR: HHP acts as a reliable and potent inducer of ICD in human tumor cells and the key features of the endoplasmic reticulum stress‐mediated apoptotic pathway, such as reactive oxygen species production, phosphorylation of the translation initiation factor eIF2α and activation of caspase‐8 were activated by HHP treatment.
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Primary Sjögren syndrome in the paediatric age: a multicentre survey.

TL;DR: Recurrent parotid swelling is a common feature of primary Sjögren syndrome in childhood and often occurs as a presenting feature and Sicca symptoms may be rarer.