J
Jo Vandesompele
Researcher at Ghent University
Publications - 406
Citations - 67052
Jo Vandesompele is an academic researcher from Ghent University. The author has contributed to research in topics: Neuroblastoma & microRNA. The author has an hindex of 88, co-authored 383 publications receiving 59368 citations. Previous affiliations of Jo Vandesompele include Washington University in St. Louis & Ghent University Hospital.
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Journal ArticleDOI
The Digital MIQE Guidelines: Minimum Information for Publication of Quantitative Digital PCR Experiments
Jim F. Huggett,Carole A. Foy,Vladimir Benes,Kerry R. Emslie,Jeremy A. Garson,Ross J. Haynes,Jan Hellemans,Mikael Kubista,Reinhold Mueller,Tania Nolan,Michael W. Pfaffl,Gregory L. Shipley,Jo Vandesompele,Carl T. Wittwer,Stephen A. Bustin +14 more
TL;DR: This report addresses known requirements for dPCR that have already been identified during this early stage of its development and commercial implementation and presents the Minimum Information for Publication of Quantitative Digital PCR Experiments guidelines.
Journal ArticleDOI
How to do successful gene expression analysis using real-time PCR
TL;DR: The key message is that quality assurance and quality control are essential throughout the entire RT-qPCR workflow; from living cells, over extraction of nucleic acids, storage, various enzymatic steps such as DNase treatment, reverse transcription and PCR amplification, to data-analysis and finally reporting.
Journal ArticleDOI
Promoting coherent minimum reporting guidelines for biological and biomedical investigations: the MIBBI project
Chris F. Taylor,Chris F. Taylor,Dawn Field,Susanna-Assunta Sansone,Susanna-Assunta Sansone,Jan Aerts,Rolf Apweiler,Michael Ashburner,Catherine A. Ball,Pierre-Alain Binz,Molly Bogue,Timothy F. Booth,Alvis Brazma,Ryan R. Brinkman,Adam Clark,Eric W. Deutsch,Oliver Fiehn,Jennifer Fostel,Peter Ghazal,Frank Gibson,Tanya Gray,Graeme R. Grimes,John M. Hancock,Nigel Hardy,Henning Hermjakob,Randall K. Julian,Matthew D. Kane,Carsten Kettner,Christopher R. Kinsinger,Eugene Kolker,Martin Kuiper,Nicolas Le Novère,Jim Leebens-Mack,Suzanna E. Lewis,Phillip Lord,Ann-Marie Mallon,Nishanth Marthandan,Hiroshi Masuya,Ruth McNally,Alexander Mehrle,Norman Morrison,Sandra Orchard,John Quackenbush,James M. Reecy,Donald G. Robertson,Philippe Rocca-Serra,Henry Rodriguez,Heiko Rosenfelder,Javier Santoyo-Lopez,Richard H. Scheuermann,Daniel Schober,Barry Smith,Jason Snape,Christian J. Stoeckert,Keith F. Tipton,Peter Sterk,Andreas Untergasser,Jo Vandesompele,Stefan Wiemann +58 more
TL;DR: The Minimum Information for Biological and Biomedical Investigations (MIBBI) project aims to foster the coordinated development of minimum-information checklists and provide a resource for those exploring the range of extant checklists.
Journal ArticleDOI
Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study
Pieter Mestdagh,Nicole Hartmann,Lukas Baeriswyl,Ditte Andreasen,Nathalie Bernard,Caifu Chen,David Cheo,Petula D'Andrade,Mike DeMayo,Lucas Dennis,Stefaan Derveaux,Yun Feng,Stephanie Fulmer-Smentek,Bernhard Gerstmayer,Julia S. Gouffon,Chris Grimley,Eric Lader,Kathy Y. Lee,Shujun Luo,Peter Mouritzen,Aishwarya Narayanan,Sunali Patel,Sabine Peiffer,Silvia Rüberg,Gary P. Schroth,Dave Schuster,Jonathan M Shaffer,Elliot J Shelton,Scott Silveria,Umberto Ulmanella,Vamsi Veeramachaneni,Frank Staedtler,Thomas Peters,Toumy Guettouche,Linda Wong,Jo Vandesompele +35 more
TL;DR: The results indicate that each method for analysis of microRNA expression has its strengths and weaknesses, which help to guide informed selection of a quantitative microRNA gene expression platform for particular study goals.
Journal ArticleDOI
Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma
Nick Bown,Simon Cotterill,Maria Lastowska,Seamus O'Neill,Adj Pearson,Dominique Plantaz,M Meddeb,Gisèle Danglot,C. Brinkschmidt,Holger Christiansen,Genevieve Laureys,Franki Speleman,J.C. Nicholson,Alain Bernheim,David R Betts,Jo Vandesompele,N. Van Roy +16 more
TL;DR: Gain of chromosome segment 17q21-qter is an important prognostic factor in children with neuroblastoma and was a significant predictive factor for adverse outcome in univariate analysis and in multivariate analysis.