J
Joanna Hauser
Researcher at Poznan University of Medical Sciences
Publications - 16
Citations - 467
Joanna Hauser is an academic researcher from Poznan University of Medical Sciences. The author has contributed to research in topics: Major depressive disorder & Genetic association. The author has an hindex of 12, co-authored 16 publications receiving 397 citations.
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Journal ArticleDOI
Glucocorticoid receptor polymorphism is associated with major depression and predominance of depression in the course of bipolar disorder
Aleksandra Szczepankiewicz,Anna Leszczynska-Rodziewicz,Joanna Pawlak,Aleksandra Rajewska-Rager,Monika Dmitrzak-Weglarz,Monika Wilkosc,Maria Skibinska,Joanna Hauser +7 more
TL;DR: Polymorphisms of NR3C1 gene analyzed in this study may modify susceptibility to major depressive disorder and seem to influence the course of bipolar disorder.
Journal ArticleDOI
Pharmacogenetics of antidepressant response: a polygenic approach
Judit García-González,Katherine E. Tansey,Joanna Hauser,Neven Henigsberg,Wolfgang Maier,Ole Mors,Anna Placentino,Marcella Rietschel,Daniel Souery,Tina Žagar,Piotr M. Czerski,Borut Jerman,Henriette N. Buttenschøn,Thomas G. Schulze,Astrid Zobel,Anne Farmer,Katherine J. Aitchison,Ian W. Craig,Peter McGuffin,Michel Giupponi,Nader Perroud,Guido Bondolfi,David M. Evans,Michael Conlon O'Donovan,Tim J Peters,Jens R. Wendland,Glyn Lewis,Shitij Kapur,Roy H. Perlis,Volker Arolt,Katharina Domschke,Gerome Breen,Charles Curtis,Lee Sang-Hyuk,Carol Kan,Stephen Newhouse,Hamel Patel,Bernhard T. Baune,Rudolf Uher,Cathryn M. Lewis,Chiara Fabbri +40 more
TL;DR: The genetic liability to MDD or schizophrenia did not predict response to antidepressants, suggesting differences between the genetic component of depression and treatment response, and larger or more homogeneous studies will be necessary to obtain a polygenic predictor of antidepressant response.
Journal ArticleDOI
New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation
Chiara Fabbri,Katherine E. Tansey,Roy H. Perlis,Joanna Hauser,Neven Henigsberg,Wolfgang Maier,Ole Mors,Anna Placentino,Marcella Rietschel,Daniel Souery,Gerome Breen,Charles Curtis,Lee Sang-Hyuk,Stephen Newhouse,Hamel Patel,Michel Guipponi,Nader Perroud,Guido Bondolfi,Michael Conlon O'Donovan,Glyn Lewis,Joanna M. Biernacka,Richard M. Weinshilboum,Anne Farmer,Katherine J. Aitchison,Ian W. Craig,Peter McGuffin,Rudolf Uher,Cathryn M. Lewis +27 more
TL;DR: A meta-analysis of Genome-Based Therapeutic Drugs for Depression (GENDEP) and Sequenced Treatment Alternatives to Relieve Depression (STAR*D) studies was performed at the single-nucleotide polymorphism (SNP), gene and pathway levels, and two SNPs were significantly associated with symptom improvement during citaloprams/escitalopram treatment.
Journal ArticleDOI
Clock gene variants differentiate mood disorders
Monika Dmitrzak-Weglarz,Joanna Pawlak,Malgorzata Maciukiewicz,Jerzy Moczko,Monika Wilkosc,Anna Leszczynska-Rodziewicz,Dorota Zaremba,Joanna Hauser +7 more
TL;DR: This study suggested a putative role of the CLOCK, TIM, ARNTL and PER3 and polymorphisms in MD susceptibility and confirmed necessity of performing separate analyzes for BPD and UPD patients.
Journal Article
Influence of dopaminergic and serotoninergic genes on working memory in healthy subjects.
Monika Wiłkość,Joanna Hauser,Marta Tomaszewska,Monika Dmitrzak-Weglarz,Maria Skibinska,Aleksandra Szczepankiewicz,Alina Borkowska +6 more
TL;DR: The results obtained in the study indicate that dopaminergic and serotoninergic genes may play a role in modulating the executive function and working memory processes in healthy subjects.