J
Jochen Dutzmann
Researcher at Hannover Medical School
Publications - 24
Citations - 758
Jochen Dutzmann is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Neointima & Internal medicine. The author has an hindex of 11, co-authored 17 publications receiving 467 citations.
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Journal ArticleDOI
Vasa Vasorum Angiogenesis: Key Player in the Initiation and Progression of Atherosclerosis and Potential Target for the Treatment of Cardiovascular Disease.
Daniel Sedding,Erin C. Boyle,Jasper A. F. Demandt,Judith C. Sluimer,Judith C. Sluimer,Jochen Dutzmann,Axel Haverich,Johann Bauersachs +7 more
TL;DR: The pivotal roles of endothelial permeability, neoangiogenesis, and plaque microvascularization by VV during plaque initiation, progression, and rupture are focused on.
Journal ArticleDOI
Inhibition of miR-92a improves re-endothelialization and prevents neointima formation following vascular injury.
Jan Marcus Daniel,Daniela Penzkofer,Rebecca Teske,Jochen Dutzmann,Alexander Koch,Wiebke Bielenberg,Angelika Bonauer,Reinier A. Boon,Ariane Fischer,Johann Bauersachs,Eva van Rooij,Stefanie Dimmeler,Daniel Sedding +12 more
TL;DR: It is indicated that inhibition of endothelial miR-92a attenuates neointimal lesion formation by accelerating re-endothelialization and thus represents a putative novel mechanism to enhance the functional recovery following vascular injury.
Journal ArticleDOI
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
Christoph Schultheiß,Edith Willscher,Lisa Paschold,Cornelia Gottschick,B. Klee,S. Henkes,Lidia Bosurgi,Jochen Dutzmann,Daniel Sedding,Thomas Frese,Matthias Girndt,Jessica I. Höll,Michael Gekle,Rafael T. Mikolajczyk,Mascha Binder +14 more
TL;DR: In this paper , a digital epidemiology approach was used to find post-acute sequelae of COVID-19 (PASC), predominantly consisting of fatigue, dyspnea, and concentration deficit, which persists in 60% over the mean 8-month follow-up period.
Journal ArticleDOI
Emerging translational approaches to target STAT3 signalling and its impact on vascular disease
TL;DR: Current clinical trials using highly effective and selective inhibitors of STAT3 signalling for distinct diseases, such as myelofibrosis and rheumatoid arthritis, are discussed with regard to their vascular (side-) effects and their potential to pave the way for a direct use of these molecules for the prevention or treatment of vascular diseases.
Journal ArticleDOI
Imaging of chemokine receptor CXCR4 expression in culprit and nonculprit coronary atherosclerotic plaque using motion-corrected [68Ga]pentixafor PET/CT
Thorsten Derlin,Daniel Sedding,Jochen Dutzmann,Arash Haghikia,Tobias König,L. Christian Napp,Christian Schütze,Nicole Owsianski-Hille,Hans-Jürgen Wester,Saskia Kropf,James T. Thackeray,Jens P. Bankstahl,Lilli Geworski,Tobias L. Ross,Johann Bauersachs,Frank M. Bengel +15 more
TL;DR: The basic feasibility of motion-corrected targeted PET/CT imaging of CXCR4 expression in coronary artery lesions, which was triggered by vessel wall inflammation but also by stent-induced injury, is demonstrated.