Joe D. O'Neil

TL;DR: The absence of a fixed conformation and the observation of fast dynamics are consistent with the ability of Tat protein to interact with a wide variety of proteins and nucleic acid and support the concept of a natively unfolded protein.

TL;DR: Two-dimensional two-dimensional NMR correlation spectroscopy suggests that in their transmembrane configuration both peptides adopt mixed alpha-/3(10)-helical structures which can be explained by the restraints imposed by the membranes and the bulky alpha-aminoisobutyric acid residues.

TL;DR: The observed differences in peptide orientation between zervamicin and alamethicin are discussed with reference to differences in their lengths, helical conformations, distribution of (hydroxy)proline residues, and hydrophobic moments.

TL;DR: Cadmium-113 and calcium-43 NMR spectra of Cd2+ and Ca2+ bound to the porcine intestinal calcium binding protein (ICaBP; Mr 9000) contain two resonances that have a unique chemical shift and are consequently assigned to the metal ion bound in the N-terminal site of ICaBP.

TL;DR: In this paper, a detailed induced circular dichroism (ICD) study of thin films of 5CB doped with three different gold nanoclusters was performed, and the results showed that the chiral Au nanclusters (Au2, Au3) successfully transfer chirality to the N-LC host producing a chiral nematic phase (N*) with the opposite helical sense in comparison to the pure, organic chiral dopant dispersed in the same N- LC host.