J
Joe N. Kornegay
Researcher at Texas A&M University
Publications - 181
Citations - 6819
Joe N. Kornegay is an academic researcher from Texas A&M University. The author has contributed to research in topics: Duchenne muscular dystrophy & Muscular dystrophy. The author has an hindex of 44, co-authored 179 publications receiving 6353 citations. Previous affiliations of Joe N. Kornegay include North Carolina State University & University of Georgia.
Papers
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Journal ArticleDOI
The homologue of the Duchenne locus is defective in X-linked muscular dystrophy of dogs.
Barry J. Cooper,Nena J. Winand,Hansell H. Stedman,Beth A. Valentine,Eric P. Hoffman,Louis M. Kunkel,Marion-Oronzi Scott,Kenneth H. Fischbeck,Joe N. Kornegay,Roger J. Avery,James R. Williams,Roy D. Schmickel,James E. Sylvester +12 more
TL;DR: It is reported here that dogs with CXMD faithfully mimic the phenotype of Duchenne muscular dystrophy and that they lack the Duchennes gene transcript and its protein product, dystrophin.
Journal ArticleDOI
An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy.
Nicholas J.H. Sharp,Nicholas J.H. Sharp,Joe N. Kornegay,S. D. Van Camp,Michael H. Herbstreith,S. L. Secore,S. Kettle,W. Y. Hung,C. D. Constantinou,Michael J. Dykstra,A. D. Roses,Richard J. Bartlett,Richard J. Bartlett +12 more
TL;DR: This work has demonstrated a RNA processing error in GRMD that results from a single base change in the 3' consensus splice site of intron 6, which predicts a termination of the dystrophin reading frame within its N-terminal domain in exon 8.
Journal ArticleDOI
Muscular dystrophy in a litter of golden retriever dogs
TL;DR: Clinicopathologic findings from two golden retriever dogs with an inherited, progressive, degenerative muscle disease that were studied until 27 and 40 months of age are described and potential contributing pathophysiologic mechanisms are discussed in relation to Duchenne muscular dystrophy.
Book
Handbook of Veterinary Neurology
TL;DR: Part I: Fundamentals 1. Neurologic History, Neuroanatomy, and Neurologic Examination 2. Localization of Lesions in the Nervous System 3. Disorders of Micturition 4. Confirming a Diagnosis 5. Clinical Problems: Signs and Symptoms.
Journal ArticleDOI
Analysis of Survival in a Retrospective Study of 86 Dogs with Brain Tumors
TL;DR: Both the mild and moderate groups had a more favorable prognosis compared with dogs who had severe initial neurologic impairment, and those dogs who were treated with cobalt-60 radiation, with or without other combinations of therapy, lived significantly longer than those who received surgery, or dogs who received symptomatic treatment.