J
Joel K. Greenson
Researcher at University of Michigan
Publications - 207
Citations - 20776
Joel K. Greenson is an academic researcher from University of Michigan. The author has contributed to research in topics: Cancer & Pancreatic cancer. The author has an hindex of 70, co-authored 200 publications receiving 18812 citations. Previous affiliations of Joel K. Greenson include Johns Hopkins University & University of Pittsburgh.
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Journal ArticleDOI
A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
Chun-Tao Wai,Joel K. Greenson,Robert J. Fontana,John D. Kalbfleisch,Jorge A. Marrero,Hari S. Conjeevaram,Anna S.F. Lok +6 more
TL;DR: It is shown that a simple index using readily available laboratory results can identify CHC patients with significant fibrosis and cirrhosis with a high degree of accuracy and may decrease the need for staging liver biopsy specimens among patients with CHC.
Journal ArticleDOI
Reproducibility of the diagnosis of dysplasia in Barrett esophagus: A reaffirmation
Elizabeth A. Montgomery,Mary P. Bronner,John R. Goldblum,Joel K. Greenson,Marian M. Haber,John Hart,Laura W. Lamps,Gregory Y. Lauwers,Audrey J. Lazenby,David N. Lewin,Marie E. Robert,Alicia Y. Toledano,Yu Shyr,K. A. Y. Washington +13 more
TL;DR: Both intraobserver and interobserver variation improved overall after the application of a modified grading system developed at a consensus conference but not in separation of BE, IND, and LGD.
Journal ArticleDOI
Statins and the Risk of Colorectal Cancer
Jenny N. Poynter,Stephen B. Gruber,Peter D.R. Higgins,Ronit Almog,Joseph D. Bonner,Hedy S. Rennert,Marcelo Low,Joel K. Greenson,Gad Rennert +8 more
TL;DR: The use of statins was associated with a 47 percent relative reduction in the risk of colorectal cancer after adjustment for other known risk factors, and the absolute risk reduction is likely low.
Journal Article
Molecular Profiling of Pancreatic Adenocarcinoma and Chronic Pancreatitis Identifies Multiple Genes Differentially Regulated in Pancreatic Cancer
Craig D. Logsdon,Diane M. Simeone,Charles E. Binkley,Thiruvengadam Arumugam,Joel K. Greenson,Thomas J. Giordano,David E. Misek,Samir M. Hanash +7 more
TL;DR: In this article, microarray data were used to profile gene expression in pancreatic adenocarcinoma (10), pancreatic cancer cell lines (7), chronic pancreatitis (5), and normal pancreas (5).
Journal ArticleDOI
The Histone Deacetylase SIRT6 Is a Tumor Suppressor that Controls Cancer Metabolism
Carlos Sebastian,Bernadette M. M. Zwaans,Dafne Magalí Silberman,Dafne Magalí Silberman,Melissa Gymrek,Alon Goren,Lei Zhong,Oren Ram,Jessica Truelove,Alexander R. Guimaraes,Debra Toiber,Claudia Cosentino,Joel K. Greenson,Alasdair I. MacDonald,Liane M. McGlynn,Fraser Maxwell,Joanne Edwards,Sofia Giacosa,Ernesto Guccione,Ralph Weissleder,Bradley E. Bernstein,Aviv Regev,Aviv Regev,Aviv Regev,Paul G. Shiels,David B. Lombard,Raul Mostoslavsky +26 more
TL;DR: SIRT6 is identified as a tumor suppressor that regulates aerobic glycolysis in cancer cells and functions as a regulator of ribosome metabolism by corepressing MYC transcriptional activity, highlighting SIRT6 as a critical modulator of cancer metabolism.