J
Johanna Emgård
Researcher at Karolinska University Hospital
Publications - 12
Citations - 2180
Johanna Emgård is an academic researcher from Karolinska University Hospital. The author has contributed to research in topics: T cell & Cell activation. The author has an hindex of 8, co-authored 10 publications receiving 1329 citations. Previous affiliations of Johanna Emgård include Karolinska Institutet.
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Journal ArticleDOI
Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19.
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Lars Eriksson,Jan-Inge Henter,Anders Sönnerborg,Tobias Allander,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +29 more
TL;DR: It is shown that SARS-CoV-2 elicits robust, broad and highly functional memory T cell responses, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19.
Posted ContentDOI
Robust T cell immunity in convalescent individuals with asymptomatic or mild COVID-19
Takuya Sekine,André Perez-Potti,Olga Rivera-Ballesteros,Kristoffer Strålin,Jean-Baptiste Gorin,Annika Olsson,Sian Llewellyn-Lacey,Habiba Kamal,Gordana Bogdanovic,Sandra Muschiol,David J. Wullimann,Tobias Kammann,Johanna Emgård,Tiphaine Parrot,Elin Folkesson,Olav Rooyackers,Olav Rooyackers,Lars Eriksson,Lars Eriksson,Anders Sönnerborg,Tobias Allander,Tobias Allander,Jan Albert,Jan Albert,Morten Nielsen,Jonas Klingström,Sara Gredmark-Russ,Niklas K. Björkström,Johan K. Sandberg,David Price,Hans-Gustaf Ljunggren,Soo Aleman,Marcus Buggert +32 more
TL;DR: The collective dataset shows that SARS-CoV-2 elicits robust memory T cell responses akin to those observed in the context of successful vaccines, suggesting that natural exposure or infection may prevent recurrent episodes of severe COVID-19 also in seronegative individuals.
Journal ArticleDOI
MAIT cell activation and dynamics associated with COVID-19 disease severity.
Tiphaine Parrot,Jean-Baptiste Gorin,Andrea Ponzetta,Kimia T. Maleki,Tobias Kammann,Johanna Emgård,André Perez-Potti,Takuya Sekine,Olga Rivera-Ballesteros,Sara Gredmark-Russ,Olav Rooyackers,Olav Rooyackers,Elin Folkesson,Elin Folkesson,Lars Eriksson,Lars Eriksson,Anna Norrby-Teglund,Hans-Gustaf Ljunggren,Niklas K. Björkström,Soo Aleman,Soo Aleman,Marcus Buggert,Jonas Klingström,Kristoffer Strålin,Kristoffer Strålin,Johan K. Sandberg +25 more
TL;DR: Findings indicate that MAIT cells are engaged in the immune response against SARS-CoV-2 and suggest their possible involvement in COVID-19 immunopathogenesis.
Journal ArticleDOI
Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation.
Johanna Emgård,Hana Kammoun,Bethania García-Cassani,Julie Chesné,Sara M. Parigi,Jean-Marie Jacob,Hung-Wei Cheng,Elza Evren,Srustidhar Das,Paulo Czarnewski,Natalie Sleiers,Felipe Melo-Gonzalez,Egle Kvedaraite,Mattias Svensson,Elke Scandella,Matthew R. Hepworth,Samuel Huber,Burkhard Ludewig,Lucie Peduto,Lucie Peduto,Eduardo J. Villablanca,Henrique Veiga-Fernandes,João Pereira,Richard A. Flavell,Richard A. Flavell,Tim Willinger,Tim Willinger +26 more
TL;DR: It is found that GPR183 and oxysterols control the localization and LTi function of ILC3s and thereby promote the formation of colonic lymphoid tissues in the steady state and inflammation.
Journal ArticleDOI
Tissue-resident MAIT cell populations in human oral mucosa exhibit an activated profile and produce IL-17.
Michał J. Sobkowiak,Haleh Davanian,Robert Heymann,Robert Heymann,Anna Gibbs,Johanna Emgård,Joana Dias,Soo Aleman,Carina Kruger-Weiner,Markus Moll,Annelie Tjernlund,Edwin Leeansyah,Edwin Leeansyah,Margaret Chen,Johan K. Sandberg +14 more
TL;DR: Oral mucosal MAIT cells form a part of the oral mucosal T cell compartment, where they exhibit a tissue‐resident‐activated profile biased toward IL‐17 production, as assessed by polyclonal stimulus and compared to tissue nonresident and circulating populations.