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John A. Oates

Researcher at Vanderbilt University

Publications -  426
Citations -  46735

John A. Oates is an academic researcher from Vanderbilt University. The author has contributed to research in topics: Prostaglandin & Arachidonic acid. The author has an hindex of 98, co-authored 425 publications receiving 45285 citations. Previous affiliations of John A. Oates include University of Colorado Boulder & University of Tokushima.

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Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework*

TL;DR: Biomarker measurements provide an avenue for researchers to gain a mechanistic understanding of the differences in clinical response that may be influenced by uncontrolled variables (for example, drug metabolism).
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Increase in circulating products of lipid peroxidation (F2-isoprostanes) in smokers. Smoking as a cause of oxidative damage.

TL;DR: The increased levels of F2-isoprostanes in the circulation of persons who smoke support the hypothesis that smoking can cause the oxidative modification of important biologic molecules in vivo.
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Effects of caffeine on plasma renin activity, catecholamines and blood pressure.

TL;DR: Under the conditions of study caffeine was a potent stimulator of plasma renin activity and adrenomedullary secretion and whether habitual ingestion has similar effects remains to be determined.