抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Surface plasmons are waves that propagate along the surface of a conductor. By altering the structure of a metal's surface, the properties of surface plasmons--in particular their interaction with light--can be tailored, which offers the potential for developing new types of photonic device. This could lead to miniaturized photonic circuits with length scales that are much smaller than those currently achieved. Surface plasmons are being explored for their potential in subwavelength optics, data storage, light generation, microscopy and bio-photonics.

/pdf/surface-plasmon-subwavelength-optics-5e55p12p4o.pdf

Surface plasmon subwavelength optics

We present experimental scattering data at microwave frequencies on a structured metamaterial that exhibits a frequency band where the effective index of refraction (n) is negative. The material consists of a two-dimensional array of repeated unit cells of copper strips and split ring resonators on interlocking strips of standard circuit board material. By measuring the scattering angle of the transmitted beam through a prism fabricated from this material, we determine the effective n, appropriate to Snell's law. These experiments directly confirm the predictions of Maxwell's equations that n is given by the negative square root of epsilon.mu for the frequencies where both the permittivity (epsilon) and the permeability (mu) are negative. Configurations of geometrical optical designs are now possible that could not be realized by positive index materials.

/pdf/experimental-verification-of-a-negative-index-of-refraction-37hlxn3tta.pdf

Experimental Verification of a Negative Index of Refraction

We show that microstructures built from nonmagnetic conducting sheets exhibit an effective magnetic permeability /spl mu//sub eff/, which can be tuned to values not accessible in naturally occurring materials, including large imaginary components of /spl mu//sub eff/. The microstructure is on a scale much less than the wavelength of radiation, is not resolved by incident microwaves, and uses a very low density of metal so that structures can be extremely lightweight. Most of the structures are resonant due to internal capacitance and inductance, and resonant enhancement combined with compression of electrical energy into a very small volume greatly enhances the energy density at critical locations in the structure, easily by factors of a million and possibly by much more. Weakly nonlinear materials placed at these critical locations will show greatly enhanced effects raising the possibility of manufacturing active structures whose properties can be switched at will between many states.

/pdf/magnetism-from-conductors-and-enhanced-nonlinear-phenomena-2fpnoamwae.pdf

Magnetism from conductors and enhanced nonlinear phenomena

The emerging field of plasmonics has yielded methods for guiding and localizing light at the nanoscale, well below the scale of the wavelength of light in free space. Now plasmonics researchers are turning their attention to photovoltaics, where design approaches based on plasmonics can be used to improve absorption in photovoltaic devices, permitting a considerable reduction in the physical thickness of solar photovoltaic absorber layers, and yielding new options for solar-cell design. In this review, we survey recent advances at the intersection of plasmonics and photovoltaics and offer an outlook on the future of solar cells based on these principles.

Plasmonics for improved photovoltaic devices

The authors use the theory of the symmetric group to construct a generalised transfer matrix from which they can obtain the Lyapunov exponents of the original transfer matrix and the localisation lengths for an electron in a random potential They compare their results with those of numerical simulations The generalised transfer matrix has infinite dimensions but can in practice be truncated to finite dimensions In the limit of an infinite matrix the theory is exact

https://iopscience.iop.org/article/10.1088/0953-8984/1/19/002/pdf

Electron localisation, Lyapunov exponents and the symmetric group

The determination of surface chemical bonds has involved an interplay between theory and experiment. Two major techniques, I.e.e.d. and s.e.X.a.f.s., are discussed and some of their limitations analysed. Finally, I look forward to the development of other methods that will further extend our powers to unravel surface chemical bonding.

Theoretical Aspects of the Nature of the Surface Chemical Bond

A method is presented of calculating emitted intensities of angular resolved emission based on the so-called 'chain method' of Pendry and Gard (1975). All final state lattice scattering effects are included in the formalism. The method is expected to have application particularly at emission energies above the normal 'Low Energy' range (0-250 eV). The method is illustrated by application to angularly resolved X-ray core level emission.

The application of the chain method to electron emission

Apparatus, methods, and systems provide conversion of evanescent electromagnetic waves to non-evanescent electromagnetic waves and/or conversion of non-evanescent electromagnetic waves to evanescent electromagnetic waves. In some approaches the conversion includes propagation of electromagnetic waves within an indefinite electromagnetic medium, and the indefinite medium may include an artificially-structured material such as a layered structure or other metamaterial.

Evanescent electromagnetic wave conversion apparatus and methods

Symmetry deepens our insight into a physical system and its interplay with topology enables the discovery of topological phases. Symmetry analysis is conventionally performed either in the physical space of interest, or in the corresponding reciprocal space. Here we borrow the concept of virtual space from transformation optics to demonstrate how a certain class of symmetries can be visualised in a transformed, spectrally related coordinate space, illuminating the underlying topological transitions. By projecting a plasmonic system in a higher-dimensional virtual space onto a lower-dimensional system in real space, we show how transformation optics allows us to construct a topologically non-trivial system by inspecting its modes in the virtual space. Interestingly, we find that the topological invariant can be controlled via the singularities in the conformal mapping, enabling the intuitive engineering of edge states. The confluence of transformation optics and topology here can be generalized to other wave realms beyond photonics. Visualizing and studying topological features is becoming crucial to develop new generation topological systems. Here the authors provide the theoretical and numerical demonstration of the potential of transformation optics connecting the virtual space to the physical space of lower dimension via conformal mapping.

John B. Pendry

Papers

Electron localisation, Lyapunov exponents and the symmetric group

Theoretical Aspects of the Nature of the Surface Chemical Bond

The application of the chain method to electron emission

Evanescent electromagnetic wave conversion apparatus and methods

Revealing topology with transformation optics.