John D. Dickinson

TL;DR: It is indicated that autophagy is essential for airway mucus secretion in a type 2, IL13-dependent immune disease process and thereby provide a novel therapeutic strategy for attenuating airway obstruction in hypersecretory inflammatory diseases such as asthma, chronic obstructive pulmonary disease, and cystic fibrosis lung disease.

TL;DR: Emerging laboratory data suggest that early in the course of septic shock, the pharmacokinetics of common broad spectrum antibiotics may be significantly altered due to increased volumes of distribution having dosing implications for antibiotics in sepsis.

TL;DR: This chapter discusses the application of mouse tracheal epithelial cell cultures for the study of asthma biology with a major advantage of this system is the ability to use airway epithelial cells from mice with defined genetic backgrounds.

TL;DR: CLL/SLL patients undergoing allogeneic SCT had a higher incidence of early treatment related mortality, mainly from regimen related toxicity and infection and a subgroup analysis suggests pts with CLL appear to have an inferior PFS compared with pts with SLL.

TL;DR: Plasma BAFF level was significantly higher in the group with cGVHD compared to normal plasma donors and post autologous stem cell transplant breast cancer patients, and the role of BAFF expression in the context of immune reconstitution, and allogeneic GVL/GVHD is not yet understood.