J
John G. Golfinos
Researcher at New York University
Publications - 180
Citations - 9084
John G. Golfinos is an academic researcher from New York University. The author has contributed to research in topics: Radiosurgery & Medicine. The author has an hindex of 44, co-authored 154 publications receiving 7803 citations. Previous affiliations of John G. Golfinos include St. Joseph's Hospital and Medical Center.
Papers
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Journal ArticleDOI
The natural history of familial cavernous malformations: results of an ongoing study.
Joseph M. Zabramski,Thomas M. Wascher,Robert F. Spetzler,B. A. Johnson,John G. Golfinos,Burton P. Drayer,Ben Brown,Daniel Rigamonti,G. Brown +8 more
TL;DR: It is demonstrated that the familial form of cavernous malformations is a dynamic disease; serial MR images revealed changes in the number, size, and imaging characteristics of lesions consistent with acute or resolving hemorrhage, and that significant changes in neurological symptoms warrant repeat MR imaging.
Journal ArticleDOI
Transforming fusions of FGFR and TACC genes in human glioblastoma
Devendra Singh,Joseph M. Chan,Pietro Zoppoli,Francesco Niola,Francesco Niola,Ryan J. Sullivan,Angelica Castano,Eric Minwei Liu,Jonathan Reichel,Jonathan Reichel,Paola Porrati,Serena Pellegatta,Kunlong Qiu,Zhibo Gao,Michele Ceccarelli,Riccardo Riccardi,Daniel J. Brat,Abhijit Guha,Kenneth Aldape,John G. Golfinos,David Zagzag,Tom Mikkelsen,Gaetano Finocchiaro,Anna Lasorella,Raul Rabadan,Antonio Iavarone +25 more
TL;DR: In mice, FGFR inhibitors slowed the growth of tumors driven by the TACC-FGFR gene, suggesting that a subset of glioblastoma patients may benefit from these types of drugs, and a fusion gene detected in a small subset of human brain tumors encodes a potentially druggable target.
Journal ArticleDOI
Glial neoplasms: dynamic contrast-enhanced T2*-weighted MR imaging.
Edmond A. Knopp,Soonmee Cha,Glyn Johnson,Avi Mazumdar,John G. Golfinos,David Zagzag,Douglas C. Miller,Patrick J. Kelly,Irvin I. Kricheff +8 more
TL;DR: Echo-planar perfusion imaging is useful in the preoperative assessment of tumor grade and in providing diagnostic information not available with conventional MR imaging.
Journal ArticleDOI
Gliomas: Predicting Time to Progression or Survival with Cerebral Blood Volume Measurements at Dynamic Susceptibility-weighted Contrast-enhanced Perfusion MR Imaging
Meng Law,Robert J. Young,James S. Babb,Nicole Peccerelli,Sophie Chheang,Michael L. Gruber,Douglas C. Miller,John G. Golfinos,David Zagzag,Glyn Johnson +9 more
TL;DR: Dynamic susceptibility-weighted contrast material-enhanced perfusion MR imaging can be used to predict median time to progression in patients with gliomas, independent of pathologic findings.
Journal Article
Comparison of cerebral blood volume and vascular permeability from dynamic susceptibility contrast-enhanced perfusion MR imaging with glioma grade.
Meng Law,Stanley Yang,James S. Babb,James S. Babb,Edmond A. Knopp,John G. Golfinos,David Zagzag,Glyn Johnson +7 more
TL;DR: In this paper, the associations between relative cerebral blood volume (rCBV) and vascular permeability (Ktrans) derived from dynamic, susceptibility-weighted, contrastenhanced (DSC) MR imaging and tumor grade and between rCBV and Ktrans were assessed.