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John Milne

Bio: John Milne is an academic researcher from University of Ottawa. The author has contributed to research in topics: Raman spectroscopy & Hydrochloric acid. The author has an hindex of 13, co-authored 38 publications receiving 507 citations.

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Book ChapterDOI
John Milne1
01 Jan 1978

60 citations

Journal ArticleDOI
John Milne1
TL;DR: The nature of 2/1 Cl/Se and Br/Se stoichiometric mixtures in acetonitrile has been studied by UV-visible and Raman spectroscopy as mentioned in this paper.

44 citations

Journal ArticleDOI
TL;DR: In this paper, the 77Se NMR spectra of solutions with stoichiometries near those for SeX2 and Se2X2 (X = Br, Cl) formation in aprotic solvents of varying basicity have been recorded.

44 citations

Journal ArticleDOI
TL;DR: In this paper, the dissociation constant of trifluoroacetic acid in aqueous solution has been determined at 25°C by electrical conductivity (0.65 mol-l−1) and at 0°c by cryoscopy (1.98 mol−1).
Abstract: The dissociation constant of trifluoroacetic acid in aqueous solution has been determined at 25°C by electrical conductivity (0.65 mol-l−1) and at 0°C by cryoscopy (1.05 mol-l−1) and electrical conductivity (0.98 mol-l−1). The good agreement between the values of the constant determined by cryoscopy and conductivity at 0°C lends confidence to the value at 25°C determined by electrical conductivity. The constant determined at 25°C is in reasonable agreement with values determined by differential refractometry (0.92 mol-l−1) and from acidity function data (0.80 mol-l−1) reported by other workers. This work renews confidence in the electrical conductivity method for determining dissociation constants of moderately strong acids.

36 citations

Journal ArticleDOI
TL;DR: Raman and Se-77 NMR spectroscopy confirm that when selenous acid is reduced by thiosulfate in water selenopentathionate and tetrathionates are formed.
Abstract: Raman and Se-77 NMR spectroscopy confirm that when selenous acid is reduced by thiosulfate in water selenopentathionate and tetrathionate are formed.Depending upon the stoichiometry and pH, two iso...

36 citations


Cited by
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Journal ArticleDOI
TL;DR: While the book is a standard fixture in most chemical and physical laboratories, including those in medical centers, it is not as frequently seen in the laboratories of physician's offices (those either in solo or group practice), and I believe that the Handbook can be useful in those laboratories.
Abstract: There is a special reason for reviewing this book at this time: it is the 50th edition of a compendium that is known and used frequently in most chemical and physical laboratories in many parts of the world. Surely, a publication that has been published for 56 years, withstanding the vagaries of science in this century, must have had something to offer. There is another reason: while the book is a standard fixture in most chemical and physical laboratories, including those in medical centers, it is not as frequently seen in the laboratories of physician's offices (those either in solo or group practice). I believe that the Handbook can be useful in those laboratories. One of the reasons, among others, is that the various basic items of information it offers may be helpful in new tests, either physical or chemical, which are continuously being published. The basic information may relate

2,493 citations

Journal ArticleDOI
TL;DR: In this article, the main characteristics of the solution chemistry of antimony in relation to its behaviour and fate in natural waters are discussed based on a careful and systematic examination of a comprehensive collection of solution equilibrium and environmentally oriented studies, some published more than 100 years ago.

599 citations

Journal ArticleDOI
TL;DR: In this article, a review of the important advances made during these last years in the mechanistic understanding of processes which govern selenium cycling and bioavailability, such as adsorption at the mineral/water interface, precipitation of elemental Selenium, or bioavailability of nanoscaled precipitates, is presented.
Abstract: Selenium is usually known as the ‘double-edged sword element' for its dual toxic and beneficial character to health. Since the pioneer works by Schwarz and Foltz on the relationships between selenium deficiency and liver, muscle and heart diseases, many efforts have been undertaken to better understand the role of selenium in health. At the same time, an increasing number of publications have appeared during these last years on the selenium physico–chemical interactions within the environment. Both types of research represent ongoing efforts to correctly estimate the bioavailability of selenium species for health and the environment. Redox reactions, diffusion, adsorption and precipitation processes or interactions with organic matter and biota govern the speciation and mobility of selenium in the environment. This review intends to emphasize and collect the important advances made during these last years in the mechanistic understanding of processes which govern selenium cycling and bioavailability, like adsorption at the mineral/water interface, precipitation of elemental selenium, or bioavailability of nanoscaled precipitates. The advent of powerful spectroscopic techniques, like X-ray absorption spectroscopy, has allowed the structural description of adsorption and substitution processes that selenium undergoes in a variety of minerals. These and other structural details about selenium precipitates are reviewed here, together with their relationships to the bioavailability of the element in the environment.

380 citations

Journal ArticleDOI
TL;DR: Traditional and modern synthetic routes to small-molecule fluorophores are surveyed and recent biological insights attained with customized fluorescent probes are highlighted to inspire the design and creation of new high-precision tools that empower chemical biologists.
Abstract: Small-molecule fluorophores manifest the ability of chemistry to solve problems in biology. As we noted in a previous review (Lavis, L. D.; Raines, R. T. ACS Chem. Biol. 2008, 3, 142–155), the extant collection of fluorescent probes is built on a modest set of “core” scaffolds that evolved during a century of academic and industrial research. Here, we survey traditional and modern synthetic routes to small-molecule fluorophores and highlight recent biological insights attained with customized fluorescent probes. Our intent is to inspire the design and creation of new high-precision tools that empower chemical biologists.

376 citations