John N. Low

Bio: John N. Low is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Hydrogen bond & Molecule. The author has an hindex of 18, co-authored 494 publications receiving 2206 citations. Previous affiliations of John N. Low include University of St Andrews & University of Dundee.

Control of the reaction between 2-aminobenzothiazoles and Mannich bases. Synthesis of pyrido[2,1-b][1,3]benzothiazoles versus [1,3]benzothiazolo[2,3-b]quinazolines

Abstract: Reactions between 2-aminobenzothiazoles and Mannich bases are observed to be selectively controlled by the steric hindrance in the latter. Pyrido[2,1-b][1,3]benzothiazoles 3 are produced with non-sterically hindered Mannich bases such as 3-(dimethylamino)propiophenone hydrochlorides 2, whilst [1,3]benzothiazolo[2,3-b]quinazolines are produced with bulky Mannich bases such as 2-(dimethylaminomethyl)tetralone 4. This is shown by reactions with 2-amino-5-(ethylsulfanyl)thiadiazole, which was previously reported to follow the former reaction pathway with 2, while the reaction with 4 follows the latter reaction pathway. The final structures are established by NMR and X-ray diffraction, thus confirming the cyclization processes.

A triclinic polymorph of benzanilide : disordered molecules form hydrogen-bonded chains

Abstract: In the P\overline 1 polymorph of benzanilide or N-phenyl­benz­amide, C13H11NO, the mol­ecules are linked into simple C(4) chains by N—H⋯O hydrogen bonds. The mol­ecules exhibit orientational disorder, but the donor and acceptor in a given hydrogen bond may occur, independently, in either the major or the minor orientation, such that all four possible N—H⋯O combinations have very similar geometries. The structure of this P\overline 1 polymorph can be related to that of a previously reported C2/c polymorph.

“Bioinformatics” 특집을 내면서

Abstract: BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

Efficient organic solar cells processed from hydrocarbon solvents

Abstract: Organic solar cells have desirable properties, including low cost of materials, high-throughput roll-to-roll production, mechanical flexibility and light weight. However, all top-performance devices are at present processed using halogenated solvents, which are environmentally hazardous and would thus require expensive mitigation to contain the hazards. Attempts to process organic solar cells from non-halogenated solvents lead to inferior performance. Overcoming this hurdle, here we present a hydrocarbon-based processing system that is not only more environmentally friendly but also yields cells with power conversion efficiencies of up to 11.7%. Our processing system incorporates the synergistic effects of a hydrocarbon solvent, a novel additive, a suitable choice of polymer side chain, and strong temperature-dependent aggregation of the donor polymer. Our results not only demonstrate a method of producing active layers of organic solar cells in an environmentally friendly way, but also provide important scientific insights that will facilitate further improvement of the morphology and performance of organic solar cells. The processing of high-performance organic solar cells usually requires environmentally hazardous solvents. Now, hydrocarbon-based processing is shown to achieve relatively high performance in a more environmentally friendly way.

CrystalExplorer: a program for Hirshfeld surface analysis, visualization and quantitative analysis of molecular crystals

Abstract: CrystalExplorer is a native cross-platform program supported on Windows, MacOS and Linux with the primary function of visualization and investigation of molecular crystal structures, especially through the decorated Hirshfeld surface and its corresponding two-dimensional fingerprint, and through the visualization of void spaces in the crystal via isosurfaces of the promolecule electron density. Over the past decade, significant changes and enhancements have been incorporated into the program, such as the capacity to accurately and quickly calculate and visualize quantitative intermolecular interactions and, perhaps most importantly, the ability to interface with the Gaussian and NWChem programs to calculate quantum-mechanical properties of molecules. The current version, CrystalExplorer21, incorporates these and other changes, and the software can be downloaded and used free of charge for academic research.