J
John Q. Trojanowski
Researcher at University of Pennsylvania
Publications - 1538
Citations - 245534
John Q. Trojanowski is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Alzheimer's disease. The author has an hindex of 226, co-authored 1467 publications receiving 213948 citations. Previous affiliations of John Q. Trojanowski include Vanderbilt University & University of California, San Francisco.
Papers
More filters
Journal ArticleDOI
Combined immunostaining of neurofilaments, neuron specific enolase, GFAP and S-100. A possible means for assessing the morphological and functional status of the enteric nervous system.
Anne E. Bishop,Francesco Carlei,Virginia M.-Y. Lee,John Q. Trojanowski,Paul J. Marangos,Doris Dahl,J.M. Polak +6 more
TL;DR: Neurofilament-, glial fibrillary acidic protein-and S-100-immunostaining can be used to reveal the enteric nervous system and its supportive cells in these three mammals.
Journal ArticleDOI
Relationship between plaques, tangles, and dystrophic processes in Alzheimer's disease
TL;DR: The conversion of soluble Aβ into insoluble amyloid fibrils and the formation of neuritic plaques may be a multi-step process involving interactions between soluble A β and pathologic co-factors some of which may be derived from degenerating neurons.
Journal ArticleDOI
τ Phosphorylation in Human, Primate, and Rat Brain: Evidence that a Pool of τ Is Highly Phosphorylated In Vivo and Is Rapidly Dephosphorylated In Vitro
Timothy D. Garver,Katherine A. Harris,Ralph A. W. Lehman,Virginia M.-Y. Lee,John Q. Trojanowski,Melvin L. Billingsley +5 more
TL;DR: The presence of a highly phosphorylated pool of τ in adult brain may modify the present hypotheses on how paired helical filaments of Alzheimer's disease are formed, and the turnover of phosphorylation sites on τ is rapid and depends on neuronal phosphatases.
Journal ArticleDOI
Microtubule stabilizing drugs for the treatment of Alzheimer's disease.
Journal ArticleDOI
A combined horseradish peroxidase-autoradiographic investigation of reciprocal connections between superior temporal gyrus and pulvinar in squirrel monkey.
TL;DR: The present communication reports on the findings with regard to the superior temporal gyrus (STG) and pulvinar in squirrel monkey using retrogradely and anterogradely transported tracers in combination.