J
John V. Williams
Researcher at University of Pittsburgh
Publications - 248
Citations - 11922
John V. Williams is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Human metapneumovirus & Respiratory tract infections. The author has an hindex of 57, co-authored 245 publications receiving 10405 citations. Previous affiliations of John V. Williams include Swiss Tropical and Public Health Institute & Vanderbilt University Medical Center.
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Journal ArticleDOI
Human metapneumovirus and lower respiratory tract disease in otherwise healthy infants and children.
John V. Williams,Paul A. Harris,Sharon J. Tollefson,Lisa L. Halburnt-Rush,Joyce M. Pingsterhaus,Kathryn M. Edwards,Peter F. Wright,James E. Crowe +7 more
TL;DR: Human metapneumovirus infection is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to that of respiratory syncytial virus.
Journal ArticleDOI
Respiratory Syncytial Virus–Associated Hospitalizations Among Children Less Than 24 Months of Age
Caroline B. Hall,Geoffrey A. Weinberg,Aaron K. Blumkin,Kathryn M. Edwards,Mary A. Staat,Andrew F. Schultz,Katherine A. Poehling,Peter G. Szilagyi,Marie R. Griffin,John V. Williams,Yuwei Zhu,Carlos G. Grijalva,Mila M. Prill,Marika K. Iwane +13 more
TL;DR: Young infants, especially those who were 1 month old, were at greatest risk of RSV hospitalization, and effective general preventive strategies will be required for all young infants, not just those with risk factors.
Journal ArticleDOI
Real-Time Reverse Transcription-PCR Assay for Comprehensive Detection of Human Rhinoviruses
Xiaoyan Lu,Brian P. Holloway,Ryan K Dare,Jane Kuypers,Shigeo Yagi,John V. Williams,Caroline B. Hall,Dean D. Erdman +7 more
TL;DR: The sensitivity and specificity of a real-time reverse transcription-PCR assay targeting the viral 5′ noncoding region defined by sequences obtained from all 100 currently recognized HRV prototype strains and 85 recently circulating field isolates was developed and clinically validated and applied in an investigation of a coincidental outbreak of HRV respiratory illness among laboratory staff.
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A novel group of rhinoviruses is associated with asthma hospitalizations
E. Kathryn Miller,Kathryn M. Edwards,Geoffrey A. Weinberg,Marika K. Iwane,Marie R. Griffin,Caroline B. Hall,Yuwei Zhu,Peter G. Szilagyi,Laura-Lee Morin,Luke Heil,Xiaoyan Lu,John V. Williams +11 more
TL;DR: Overall, HRVCs were detected in 7% of children hospitalized for fever or respiratory conditions and constituted almost half of all rhinovirus-associated hospitalizations, suggesting that this novel group causes a substantial burden of pediatric disease.
Journal ArticleDOI
Burden of Human Metapneumovirus Infection in Young Children
Kathryn M. Edwards,Yuwei Zhu,Marie R. Griffin,Geoffrey A. Weinberg,Caroline B. Hall,Peter G. Szilagyi,Mary A. Staat,Marika K. Iwane,Mila M. Prill,John V. Williams +9 more
TL;DR: HMPV infection is associated with a substantial burden of hospitalizations and outpatient visits among children throughout the first 5 years of life, especially during the first year.