J
Jon R. Gentsch
Researcher at National Center for Immunization and Respiratory Diseases
Publications - 204
Citations - 17767
Jon R. Gentsch is an academic researcher from National Center for Immunization and Respiratory Diseases. The author has contributed to research in topics: Rotavirus & Rotavirus vaccine. The author has an hindex of 70, co-authored 204 publications receiving 17025 citations. Previous affiliations of Jon R. Gentsch include All India Institute of Medical Sciences & Centers for Disease Control and Prevention.
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Journal ArticleDOI
Identification of group A rotavirus gene 4 types by polymerase chain reaction.
Jon R. Gentsch,Roger I. Glass,P. A. Woods,Vera Gouvea,M Gorziglia,J Flores,Bimal Kumar Das,Maharaj K. Bhan +7 more
TL;DR: The results suggest that gene 4 typing will be useful in providing more a complete characterization of HRV strains of epidemiologic or vaccine-related interest.
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Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG).
Jelle Matthijnssens,Max Ciarlet,Sarah M. McDonald,Houssam Attoui,Krisztián Bányai,J. Rodney Brister,Javier Buesa,Mathew D. Esona,Mary K. Estes,Jon R. Gentsch,Miren Iturriza-Gomara,Reimar Johne,Carl D. Kirkwood,Vito Martella,Peter P. C. Mertens,Osamu Nakagomi,Viviana Parreño,Mustafizur Rahman,Franco Maria Ruggeri,Linda J. Saif,Norma Santos,Andrej Steyer,Koki Taniguchi,John T. Patton,Ulrich Desselberger,Marc Van Ranst +25 more
TL;DR: With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification /G- and P-type.
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Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments.
Jelle Matthijnssens,Max Ciarlet,Mustafizur Rahman,Mustafizur Rahman,Houssam Attoui,Krisztián Bányai,Mary K. Estes,Jon R. Gentsch,Miren Iturriza-Gomara,Carl D. Kirkwood,Vito Martella,Peter P. C. Mertens,Osamu Nakagomi,John T. Patton,Franco Maria Ruggeri,Linda J. Saif,Norma Santos,Andrej Steyer,Koki Taniguchi,Ulrich Desselberger,Marc Van Ranst +20 more
TL;DR: A Rotavirus Classification Working Group (RCWG) including specialists in molecular virology, infectious diseases, epidemiology, and public health was formed, which can assist in the appropriate delineation of new genotypes, thus avoiding duplications and helping minimize errors.
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Serotype diversity and reassortment between human and animal rotavirus strains: implications for rotavirus vaccine programs.
Jon R. Gentsch,Ashley R. Laird,Brittany Bielfelt,Dixie D. Griffin,Krisztián Bányai,M. Ramachandran,Vivek Jain,Nigel A. Cunliffe,Osamu Nakagomi,Carl D. Kirkwood,Thea Kølsen Fischer,Umesh D. Parashar,Joseph S. Bresee,Baoming Jiang,Roger I. Glass +14 more
TL;DR: Strain surveillance helps to determine whether the most prevalent local strains are likely to be covered by the serotype antigens found in current vaccines, and identified globally (G9) or regionally (G5, G8, and P2A[6]) common serotypes not cover by the reassortant vaccines that have undergone efficacy trials.
Journal ArticleDOI
Rotavirus vaccines: current prospects and future challenges
Roger I. Glass,Umesh D. Parashar,Joseph S. Bresee,Reina M. Turcios,Thea Kølsen Fischer,Marc-Alain Widdowson,Baoming Jiang,Jon R. Gentsch +7 more
TL;DR: Although many scientific, programmatic, and financial challenges face the global use of rotavirus vaccines, these vaccines-and new candidates in the pipeline-hold promise to make an immediate and measurable effect to improve child health and survival from this common burden affecting all children.