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Jon Timmis

Bio: Jon Timmis is an academic researcher from University of York. The author has contributed to research in topics: Artificial immune system & Swarm robotics. The author has an hindex of 41, co-authored 284 publications receiving 8212 citations. Previous affiliations of Jon Timmis include Helsinki University of Technology & York St John University.


Papers
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Proceedings ArticleDOI
12 May 2002
TL;DR: The main features of the adaptation of an immune network model include: automatic determination of the population size, combination of local with global search, defined convergence criterion, and capability of locating and maintaining stable local optima solutions.
Abstract: This paper presents the adaptation of an immune network model, originally proposed to perform information compression and data clustering, to solve multimodal function optimization problems. The algorithm is described theoretically and empirically compared with similar approaches from the literature. The main features of the algorithm include: automatic determination of the population size, combination of local with global search (exploitation plus exploration of the fitness landscape), defined convergence criterion, and capability of locating and maintaining stable local optima solutions.

650 citations

Journal ArticleDOI
01 Aug 2003
TL;DR: This paper proposes one such framework for AIS, discusses the suitability of AIS as a novel soft computing paradigm and reviews those works from the literature that integrate AIS with other approaches, focusing ANN, EA and FS.
Abstract: Artificial immune systems (AIS) can be defined as computational systems inspired by theoretical immunology, observed immune functions, principles and mechanisms in order to solve problems. Their development and application domains follow those of soft computing paradigms such as artificial neural networks (ANN), evolutionary algorithms (EA) and fuzzy systems (FS). Despite some isolated efforts, the field of AIS still lacks an adequate framework for design, interpretation and application. This paper proposes one such framework, discusses the suitability of AIS as a novel soft computing paradigm and reviews those works from the literature that integrate AIS with other approaches, focusing ANN, EA and FS. Similarities and differences between AIS and each of the other approaches are outlined. New trends on how to create hybrids of these paradigms and what could be the benefits of this hybridization are also presented.

500 citations

Journal ArticleDOI
TL;DR: A minimalist formulation of an artificial immune system and some of its behaviour is described and a simple implementation and a suitable visualization technique are demonstrated using some trivial data and the famous 'iris' data set.
Abstract: We present a simplified view of those parts of the human immune system which can be used to provide the basis for a data analysis tool. The motivation for and reasoning behind such a model is given and the desire for a ‘transparent’ model and meaningful visualization and interpretation techniques is noted. A minimalist formulation of an artificial immune system and some of its behaviour is described. A simple implementation and a suitable visualization technique are demonstrated using some trivial data and the famous ‘iris’ data set.

404 citations

Journal ArticleDOI
TL;DR: Experimental results indicate that the revisions to the algorithm do not sacrifice accuracy while increasing the data reduction capabilities of AIRS, which is an immune-inspired supervised learning algorithm.
Abstract: This paper presents the inception and subsequent revisions of an immune-inspired supervised learning algorithm, Artificial Immune Recognition System (AIRS). It presents the immunological components that inspired the algorithm and describes the initial algorithm in detail. The discussion then moves to revisions of the basic algorithm that remove certain unnecessary complications of the original version. Experimental results for both versions of the algorithm are discussed and these results indicate that the revisions to the algorithm do not sacrifice accuracy while increasing the data reduction capabilities of AIRS.

380 citations

Journal ArticleDOI
TL;DR: The existing theoretical work on AIS is reviewed and details of the theoretical analysis for each of the three main types of AIS algorithm, clonal selection, immune network and negative selection, are given.

291 citations


Cited by
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Journal ArticleDOI
TL;DR: Machine learning addresses many of the same research questions as the fields of statistics, data mining, and psychology, but with differences of emphasis.
Abstract: Machine Learning is the study of methods for programming computers to learn. Computers are applied to a wide range of tasks, and for most of these it is relatively easy for programmers to design and implement the necessary software. However, there are many tasks for which this is difficult or impossible. These can be divided into four general categories. First, there are problems for which there exist no human experts. For example, in modern automated manufacturing facilities, there is a need to predict machine failures before they occur by analyzing sensor readings. Because the machines are new, there are no human experts who can be interviewed by a programmer to provide the knowledge necessary to build a computer system. A machine learning system can study recorded data and subsequent machine failures and learn prediction rules. Second, there are problems where human experts exist, but where they are unable to explain their expertise. This is the case in many perceptual tasks, such as speech recognition, hand-writing recognition, and natural language understanding. Virtually all humans exhibit expert-level abilities on these tasks, but none of them can describe the detailed steps that they follow as they perform them. Fortunately, humans can provide machines with examples of the inputs and correct outputs for these tasks, so machine learning algorithms can learn to map the inputs to the outputs. Third, there are problems where phenomena are changing rapidly. In finance, for example, people would like to predict the future behavior of the stock market, of consumer purchases, or of exchange rates. These behaviors change frequently, so that even if a programmer could construct a good predictive computer program, it would need to be rewritten frequently. A learning program can relieve the programmer of this burden by constantly modifying and tuning a set of learned prediction rules. Fourth, there are applications that need to be customized for each computer user separately. Consider, for example, a program to filter unwanted electronic mail messages. Different users will need different filters. It is unreasonable to expect each user to program his or her own rules, and it is infeasible to provide every user with a software engineer to keep the rules up-to-date. A machine learning system can learn which mail messages the user rejects and maintain the filtering rules automatically. Machine learning addresses many of the same research questions as the fields of statistics, data mining, and psychology, but with differences of emphasis. Statistics focuses on understanding the phenomena that have generated the data, often with the goal of testing different hypotheses about those phenomena. Data mining seeks to find patterns in the data that are understandable by people. Psychological studies of human learning aspire to understand the mechanisms underlying the various learning behaviors exhibited by people (concept learning, skill acquisition, strategy change, etc.).

13,246 citations

01 Jan 2002

9,314 citations

Journal ArticleDOI
06 Jun 1986-JAMA
TL;DR: The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or her own research.
Abstract: I have developed "tennis elbow" from lugging this book around the past four weeks, but it is worth the pain, the effort, and the aspirin. It is also worth the (relatively speaking) bargain price. Including appendixes, this book contains 894 pages of text. The entire panorama of the neural sciences is surveyed and examined, and it is comprehensive in its scope, from genomes to social behaviors. The editors explicitly state that the book is designed as "an introductory text for students of biology, behavior, and medicine," but it is hard to imagine any audience, interested in any fragment of neuroscience at any level of sophistication, that would not enjoy this book. The editors have done a masterful job of weaving together the biologic, the behavioral, and the clinical sciences into a single tapestry in which everyone from the molecular biologist to the practicing psychiatrist can find and appreciate his or

7,563 citations

01 Aug 2000
TL;DR: Assessment of medical technology in the context of commercialization with Bioentrepreneur course, which addresses many issues unique to biomedical products.
Abstract: BIOE 402. Medical Technology Assessment. 2 or 3 hours. Bioentrepreneur course. Assessment of medical technology in the context of commercialization. Objectives, competition, market share, funding, pricing, manufacturing, growth, and intellectual property; many issues unique to biomedical products. Course Information: 2 undergraduate hours. 3 graduate hours. Prerequisite(s): Junior standing or above and consent of the instructor.

4,833 citations

01 Jan 2015
TL;DR: In the second edition, the authors have reorganized the material to focus on problems, how to represent them, and then how to choose and design algorithms for different representations as discussed by the authors.
Abstract: The overall structure of this new edition is three-tier: Part I presents the basics, Part II is concerned with methodological issues, and Part III discusses advanced topics. In the second edition the authors have reorganized the material to focus on problems, how to represent them, and then how to choose and design algorithms for different representations. They also added a chapter on problems, reflecting the overall book focus on problem-solvers, a chapter on parameter tuning, which they combined with the parameter control and "how-to" chapters into a methodological part, and finally a chapter on evolutionary robotics with an outlook on possible exciting developments in this field. The book is suitable for undergraduate and graduate courses in artificial intelligence and computational intelligence, and for self-study by practitioners and researchers engaged with all aspects of bioinspired design and optimization.

4,461 citations