Jonas O. Tegenfeldt

TL;DR: It is shown that genomic-length DNA molecules imaged in nanochannels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers.

TL;DR: This paper demonstrates dielectrophoretic trapping using insulating constrictions at far lower frequencies than are feasible with metallic trapping structures because of water electrolysis, and demonstrates that electrodelessdielectrophoresis (EDEP) can be used for concentration and patterning of both single-strand and double-stranded DNA.

TL;DR: In this article, the authors made uniform arrays of nanometer scale structures using nanoimprint lithography over large areas (100 mm wafers) and sealed the nanofluidic channels by techniques based on nonuniform deposition.

TL;DR: This paper gives a few examples from the literature and from the own research in the field of miniaturized chip-based devices for DNA analysis, including dielectrophoresis for purification of DNA, artificial gel structures for rapid DNA separation, and nanofluidic channels for direct visualization of single DNA molecules.

TL;DR: Generic data analysis algorithms and a simple experimental setup are presented that provide a S/N upon protein binding that is comparable to that of state-of-the art SPR systems and the importance of utilizing changes in both peak position and magnitude is highlighted.