J
Jonathan Q. Purnell
Researcher at Oregon Health & Science University
Publications - 149
Citations - 14917
Jonathan Q. Purnell is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Insulin resistance & Diabetes mellitus. The author has an hindex of 42, co-authored 136 publications receiving 13859 citations. Previous affiliations of Jonathan Q. Purnell include University of Washington & Cardiovascular Institute of the South.
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Journal ArticleDOI
A Preprandial Rise in Plasma Ghrelin Levels Suggests a Role in Meal Initiation in Humans
David E. Cummings,Jonathan Q. Purnell,R. Scott Frayo,Karin Schmidova,Brent E. Wisse,David S. Weigle +5 more
TL;DR: The hypothesis that ghrelin plays a physiological role in meal initiation in humans is supported by the clear preprandials rise and postprandial fall in plasma ghrelIn levels.
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Plasma Ghrelin Levels after Diet-Induced Weight Loss or Gastric Bypass Surgery
David E. Cummings,David S. Weigle,R. Scott Frayo,Patricia A. Breen,Marina K. Ma,E. Patchen Dellinger,Jonathan Q. Purnell +6 more
TL;DR: The increase in the plasma ghrelin level with diet-induced weight loss is consistent with the hypothesis that gh Relin has a role in the long-term regulation of body weight.
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Evidence-Based Nutrition Principles and Recommendations for the Treatment and Prevention of Diabetes and Related Complications
Marion J. Franz,John P. Bantle,Christine A. Beebe,John D. Brunzell,Jean Louis Chiasson,Abhimanyu Garg,Lea Ann Holzmeister,Byron J. Hoogwerf,Elizabeth J. Mayer-Davis,Arshag D. Mooradian,Jonathan Q. Purnell,Madelyn L. Wheeler +11 more
TL;DR: This 2002 technical review provides principles and recommendations classified according to the level of evidence available, and grades nutrition principles into four categories based on the available evidence: those with strong supporting evidence, those with some supporting evidence), those with limited supporting evidence and those based on expert consensus.
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A high-protein diet induces sustained reductions in appetite, ad libitum caloric intake, and body weight despite compensatory changes in diurnal plasma leptin and ghrelin concentrations
David S. Weigle,Patricia A. Breen,Colleen C. Matthys,Holly S. Callahan,Kaatje Meeuws,Verna R. Burden,Jonathan Q. Purnell +6 more
TL;DR: An increase in dietary protein from 15% to 30% of energy at a constant carbohydrate intake produces a sustained decrease in ad libitum caloric intake that may be mediated by increased central nervous system leptin sensitivity and results in significant weight loss.