J
Jonathan R. Manning
Researcher at European Bioinformatics Institute
Publications - 8
Citations - 603
Jonathan R. Manning is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Expression quantitative trait loci & Genome-wide association study. The author has an hindex of 5, co-authored 8 publications receiving 251 citations.
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Journal ArticleDOI
Expression Atlas update: from tissues to single cells
Irene Papatheodorou,Pablo Moreno,Jonathan R. Manning,Alfonso Muñoz-Pomer Fuentes,Nancy George,Silvie Fexova,Nuno A. Fonseca,Anja Füllgrabe,Matthew Green,Ni Huang,Ni Huang,Laura Huerta,Haider Iqbal,Monica Jianu,Suhaib Mohammed,Lingyun Zhao,Andrew F. Jarnuczak,Simon Jupp,John C. Marioni,John C. Marioni,John C. Marioni,Kerstin B. Meyer,Robert Petryszak,Cesar Augusto Prada Medina,Carlos Talavera-López,Sarah A. Teichmann,Juan Antonio Vizcaíno,Alvis Brazma +27 more
TL;DR: Expression Atlas is extended with a new added-value service to display gene expression in single cells with the increased availability of single cell RNA-Seq datasets in the public archives.
Journal ArticleDOI
A compendium of uniformly processed human gene expression and splicing quantitative trait loci.
Nurlan Kerimov,James D. Hayhurst,Kateryna Peikova,Jonathan R. Manning,Peter Walter,Liis Kolberg,Marija Samoviča,Manoj Pandian Sakthivel,Ivan Kuzmin,Stephen J. Trevanion,Tony Burdett,Simon Jupp,Helen Parkinson,Irene Papatheodorou,Andrew D. Yates,Daniel R. Zerbino,Kaur Alasoo +16 more
TL;DR: The eQTL Catalogue as discussed by the authors is a set of gene expression quantitative trait locus (eQTL) studies published their summary statistics, which can be used to gain insight into complex human traits by downstream analyses, such as fine mapping and co-localization.
Posted ContentDOI
eQTL Catalogue: a compendium of uniformly processed human gene expression and splicing QTLs
Nurlan Kerimov,James D. Hayhurst,Jonathan R. Manning,Peter Walter,Liis Kolberg,Kateryna Peikova,Marija Samoviča,Tony Burdett,Simon Jupp,Helen Parkinson,Irene Papatheodorou,Daniel R. Zerbino,Kaur Alasoo +12 more
TL;DR: The eQTL Catalogue is presented, a resource which contains quality controlled, uniformly recomputed QTLs from 21 eQtl studies, and it is found that for matching cell types and tissues, the eZTL effect sizes are highly reproducible between studies, enabling the integrative analysis of these data.
Journal ArticleDOI
Expression Atlas update: gene and protein expression in multiple species.
Pablo Moreno,Silvie Fexova,Nancy George,Jonathan R. Manning,Zhichiao Miao,Suhaib Mohammed,Alfonso Munoz-Pomer,Anja Füllgrabe,Yalan Bi,Natassja Bush,Haider Iqbal,Upendra Kumbham,Andrey Solovyev,Lingyun Zhao,Ananth Prakash,David García-Seisdedos,Deepti J. Kundu,Shengbo Wang,Mathias Walzer,Laura Clarke,David Osumi-Sutherland,Marcela K. Tello-Ruiz,Sunita Kumari,Doreen Ware,Doreen Ware,Jana Eliasova,Mark J. Arends,Martijn C. Nawijn,Kerstin B. Meyer,Tony Burdett,John C. Marioni,Sarah A. Teichmann,Juan Antonio Vizcaíno,Alvis Brazma,Irene Papatheodorou +34 more
TL;DR: The EMBL-EBI Expression Atlas as mentioned in this paper is a knowledge base that enables researchers to answer the question of where (tissue, organism part, developmental stage, cell type) and under which conditions (disease, treatment, gender, etc) a gene or protein of interest is expressed.
Journal ArticleDOI
User-friendly, scalable tools and workflows for single-cell RNA-seq analysis
Pablo Moreno,Ni Huang,Ni Huang,Jonathan R. Manning,Suhaib Mohammed,Andrey Solovyev,Krzysztof Polanski,Wendi Bacon,Ruben Chazarra,Carlos Talavera-López,Carlos Talavera-López,Maria A. Doyle,Maria A. Doyle,Guilhem Marnier,Björn Grüning,Helena Rasche,Nancy George,Silvie Fexova,Mohamed Alibi,Zhichao Miao,Yasset Perez-Riverol,Maximilian Haeussler,Alvis Brazma,Sarah A. Teichmann,Kerstin B. Meyer,Irene Papatheodorou +25 more