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Jonathan Tersur Orasugh

Bio: Jonathan Tersur Orasugh is an academic researcher from University of Calcutta. The author has contributed to research in topics: Materials science & Graphene. The author has an hindex of 9, co-authored 16 publications receiving 221 citations.

Papers
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TL;DR: Release profiles from the CNF/chitosan matrices indicate that the drug release rate is sustained with the incorporation of CNFs, and it is believed that this new nanocarrier may be a potential choice for transdermal drug delivery systems.
Abstract: Cellulose nanofibrils (CNFs) have attracted attention as a promising material in the biomedical field because of their outstanding properties such as hydrophilicity, biocompatibility, biodegradability, and high surface area. In this work, we have prepared cellulose nanofibrils from jute fibres (JF), to develop a CNF/chitosan transdermal film for the delivery of ketorolec tromethamine (KT) where the CNFs act as an elegant nanometric carrier. The KT-loaded CNF/chitosan transdermal film matrices have been characterized by Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and X-ray diffraction (XRD) analysis. Fourier transform infrared spectroscopy (FTIR) reveals the successful KT loading into the CNF/chitosan transdermal film. Scanning electron microscopy (SEM) study shows the different morphological features of the CNF/chitosan transdermal films. The crystalline nature of the CNF/chitosan transdermal films has been analyzed by X-ray diffraction study. Release profiles from the CNF/chitosan matrices indicate that the drug release rate is sustained with the incorporation of CNFs. We believe that this new nanocarrier may be a potential choice for transdermal drug delivery systems.

62 citations

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TL;DR: The cost-effective synthesis route and efficient adsorption capacity of the nanocomposite indicate its immense potential for large-scale application in wastewater treatment.

52 citations

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TL;DR: The reinforcing nature of CNC via H-bonding in the in situ nanocomposite gel led to an increase in gel strength along with the sustained release of loaded drugs when compared with the pure PM gel.

49 citations

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TL;DR: In this article, an environment-friendly approach for the synthesis of reduced graphene oxide/nickel oxide nanocomposites (RGO/NiO NCs) was done in a microwave via in-situ co-precipitation and hydrothermal mode.

41 citations


Cited by
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31 Aug 2005
TL;DR: In this article, a high-pressure homogenizer treatment and a grinder treatment were used to fibrillate wood pulp fibers into nanofibers, which demonstrated promising properties as reinforcement material for optically transparent composites.
Abstract: The fibrillation of pulp fiber was attempted by two methods, a high-pressure homogenizer treatment and a grinder treatment. The grinder treatment resulted in the successful fibrillation of wood pulp fibers into nanofibers. The nanofibers demonstrate promising characteristics as reinforcement material for optically transparent composites. Due to the size effect, the nanofiber-reinforced composite retains the transparency of the matrix resin even at high fiber content such as 70 wt %. Since the nanofiber is an aggregate of semi-crystalline extended cellulose chains, its addition also contributes to a significant improvement in the thermal expansion properties of plastics while maintaining its ease of bending. Cellulose nanofibers have tremendous potential as a future resource since they are produced in a sustainable manner by plants, one of the most abundant organic resources on earth.

376 citations

Journal ArticleDOI
TL;DR: This review describes the new trends in nanomaterials based drug delivery systems mainly using biopolymers such as proteins (silk fibroin, collagen, gelatin and albumin) and polysaccharides (chitosan, alginate, cellulose and starch).

303 citations

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TL;DR: Three types of nanocellulose are introduced (nanocrystalline, nanofibrillar, and bacterial) and their production processes are evaluated and the selection of proper source and processing techniques for nano cellulose production is facilitated.
Abstract: Nanocellulose, as a promising natural material, has recently received much attention because of its remarkable features including recyclability, biocompatibility, low risk of toxicity, and tunable ...

139 citations

Journal ArticleDOI
TL;DR: An overview on the current state of science on nanocellulose research is provided in this article, highlighting its extraction procedures from lignocellulosic biomass, and an assessment on the emerging application of nanocellular materials with an emphasis on development of nanocomposite materials for designing environmentally sustainable products is incorporated.

127 citations

Journal ArticleDOI
TL;DR: This review article provides a comprehensive overview of different modifications made on guar gum through derivatization in the quest to make them more versatile for drug delivery applications.

115 citations