J
Jorge Luis Maria Ruiz
Researcher at University of São Paulo
Publications - 16
Citations - 374
Jorge Luis Maria Ruiz is an academic researcher from University of São Paulo. The author has contributed to research in topics: Apoptosis & Mesenchymal stem cell. The author has an hindex of 11, co-authored 15 publications receiving 309 citations. Previous affiliations of Jorge Luis Maria Ruiz include Autonomous University of Barcelona & University of the Basque Country.
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Journal ArticleDOI
Surface-modified silica nanoparticles for tumor-targeted delivery of camptothecin and its biological evaluation
P. Botella,Ibane Abasolo,Yolanda Fernández,Carlos Muniesa,Sonia Miranda,Manuel Quesada,Jorge Luis Maria Ruiz,Simó Schwartz,Avelino Corma +8 more
TL;DR: Results indicate that the SNP-CPT could be used as a robust drug delivery system for antitumoral treatments based on CPT, and boost CPT concentration in tumor vs administration of the free drug.
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Apoptotic effect of eugenol envolves G2/M phase abrogation accompanied by mitochondrial damage and clastogenic effect on cancer cell in vitro.
Paulo Luiz de Sá Júnior,Diana Aparecida Dias Câmara,André Santos Costa,Jorge Luis Maria Ruiz,Debora Levy,Ricardo A. Azevedo,Kerly Fernanda Mesquita Pasqualoto,Camila Fávero de Oliveira,Thatiana Correa de Melo,Nara Diniz Soares Pessoa,Pâmela Maria Moreira Fonseca,Alexandre Pereira,Rodrigo Pinheiro Araldi,Adilson Kleber Ferreira +13 more
TL;DR: New light is shed on the mechanisms of action of EUG suggesting a possible applicability of this phenylpropanoid as adjuvant in anti-cancer therapy.
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Anti-Angiogenic and Anti-Metastatic Activity of Synthetic Phosphoethanolamine
Adilson Kleber Ferreira,Vanessa Morais Freitas,Debora Levy,Jorge Luis Maria Ruiz,Sérgio Paulo Bydlowski,Rose Eli Grassi Rici,Otaviano Mendonça Ribeiro Filho,Gilberto Orivaldo Chierice,Durvanei Augusto Maria +8 more
TL;DR: Findings provide evidence that Pho-s is a compound that potently inhibits lung metastasis, suggesting that it is a promising novel candidate drug for future developments.
Journal ArticleDOI
Interrelationship between ATP-binding cassette transporters and oxysterols.
TL;DR: Several lines of evidence link ABC transporter functions with cholesterol and oxysterol metabolism, and how they interact with each other are discussed.
Journal ArticleDOI
Short-term effects of 7-ketocholesterol on human adipose tissue mesenchymal stem cells in vitro.
Debora Levy,Jorge Luis Maria Ruiz,Andrea Turbuck Celestino,Suelen Feitoza Silva,Adilson Kleber Ferreira,Cesar Isaac,Sérgio Paulo Bydlowski +6 more
TL;DR: The short-term cytotoxic effect of 7-ketocholesterol on MSCs derived from human adipose tissue was described and the IC50 was higher in these cells than has been observed or described in other normal or cancer cell lines.