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Jorge Sánchez

Researcher at National Autonomous University of Mexico

Publications -  69
Citations -  2637

Jorge Sánchez is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Bacillus thuringiensis & Pseudosuccinea columella. The author has an hindex of 25, co-authored 66 publications receiving 2399 citations. Previous affiliations of Jorge Sánchez include University of Valencia.

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Cadherin-like receptor binding facilitates proteolytic cleavage of helix α-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin

TL;DR: A model where receptor binding allows the efficient cleavage of α‐1 and formation of a pre‐pore oligomeric structure that is efficient in pore formation, is presented.
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Interactions of Bacillus thuringiensis crystal proteins with the midgut epithelial cells of Spodoptera frugiperda (Lepidoptera: Noctuidae).

TL;DR: Investigation of ingested B. thuringiensis ICPs on gut sections of S. frugiperda larvae revealed that CryIC and CryID toxins bound along the epithelial brush border microvilli membrane, implying that this type of interaction occurs also in vivo although it is not related to toxicity.
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Role of receptor interaction in the mode of action of insecticidal Cry and Cyt toxins produced by Bacillus thuringiensis.

TL;DR: Recently, it was proposed that Cyt1Aa synergizes or suppresses resistance to Cry toxins by functioning as a membrane-bound receptor for Cry toxin.