J
Jørgen Olsen
Researcher at University of Copenhagen
Publications - 99
Citations - 4020
Jørgen Olsen is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Gene expression & Gene expression profiling. The author has an hindex of 34, co-authored 94 publications receiving 3733 citations.
Papers
More filters
Journal ArticleDOI
A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
Kristoffer L. Egerod,Maja S. Engelstoft,Kaare V. Grunddal,Mark K. Nøhr,Anna Secher,Ichiro Sakata,Jens Pedersen,Johanne Agerlin Windeløv,Ernst-Martin Füchtbauer,Jørgen Olsen,Frank Sundler,Jan Pravsgaard Christensen,Nils Wierup,Jesper V. Olsen,Jens J. Holst,Jeffrey M. Zigman,Steen Seier Poulsen,Thue W. Schwartz +17 more
TL;DR: It is concluded that a lineage of mature enteroendocrine cells have the ability to coexpress members of a group of functionally related peptides: CCK, secretin, GIP, GLP-1, PYY, and neurotensin, suggesting a potential therapeutic target for the treatment and prevention of diabetes and obesity.
Journal ArticleDOI
Complete amino acid sequence of human intestinal aminopeptidase N as deduced from cloned cDNA
Jørgen Olsen,G M Cowell,Elaine Kønigshøfer,E. Michael Danielsen,Jette Møller,Liselotte Laustsen,Ole C. Hansen,Karen G. Welinder,Jan Engberg,Walter Hunziker,Martin Spiesst,Hans Sjöström,Ove Norén +12 more
TL;DR: The complete primary structure (967 amino acids) of an intestinal human aminopeptidase N was deduced from the sequence of a cDNA clone suggesting that the juxta‐ and intra‐membraneous parts of the molecule have been added/preserved during development.
Journal ArticleDOI
Relationship between cumulative anthracycline dose and late cardiotoxicity in childhood acute lymphoblastic leukemia.
Karsten Nysom,Kirsten Holm,Stuart R. Lipsitz,Suzanne M. Mone,Steven D. Colan,Endel J. Orav,Stephen E. Sallan,Jørgen Olsen,H Hertz,J R Jacobsen,Steven E. Lipshultz +10 more
TL;DR: Depressed left ventricular fractional shortening andleft ventricular dilatation were uncommon years after treatment of childhood leukemia when cumulative anthracycline doses were < or = 300 mg/m2.
Journal ArticleDOI
MicroRNAs and potential target interactions in psoriasis
John Robert Zibert,Marianne B. Løvendorf,Thomas Litman,Jørgen Olsen,Bogumil Kaczkowski,Lone Skov +5 more
TL;DR: The data indicate several novel important associations for miRNAs in psoriasis and in particular the miR-221/2-TIMP3 target interaction could among others play a role in the psoriatic skin pathogenesis.
Journal ArticleDOI
An upstream polymorphism associated with lactase persistence has increased enhancer activity.
TL;DR: The discovery of a functional difference between the 2 alleles at position -13910 supports the notion that the molecular difference between lactase persistence and nonpersistence is caused by the mutation at position-13910.