José A. González-Reyes

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: The authors' data illustrate the complexity of CR in the context of aging, with a clear separation of outcomes related to health and survival, highlighting complexities of translation of CR into human interventions.

TL;DR: It is shown that SRT2104, a synthetic small molecule activator of SIRT1, extends both mean and maximal lifespan of mice fed a standard diet, accompanied by improvements in health, including enhanced motor coordination, performance, bone mineral density, and insulin sensitivity associated with higher mitochondrial content and decreased inflammation.

TL;DR: This work demonstrates the active production of vesicle production by Streptococcus pneumoniae from the plasma membrane, rather than being a product from cell lysis, and shows that pneumococcus produces membrane-derived vesicles particularly enriched in lipoproteins and short-chain fatty acids.

TL;DR: The turbo ferric chelate reductase activity of Fe-deficient plants at low pH appears to be different from the constitutive ferricChelate reductor, which has been studied in intact plants of Beta vulgaris and in purified plasma membrane vesicles from the same plants.