Author
José A. Morais
Other affiliations: Royal Victoria Regional Health Centre, McGill University, Montreal General Hospital ...read more
Bio: José A. Morais is an academic researcher from McGill University Health Centre. The author has contributed to research in topics: Insulin resistance & Insulin. The author has an hindex of 47, co-authored 162 publications receiving 6935 citations. Previous affiliations of José A. Morais include Royal Victoria Regional Health Centre & McGill University.
Papers published on a yearly basis
Papers
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738 citations
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Valve Corporation1, Beth Israel Deaconess Medical Center2, McGill University Health Centre3, Population Health Research Institute4, University of Ottawa5, University of Toronto6, University of Manitoba7, Université de Montréal8, Harvard University9, Washington University in St. Louis10, Montreal Heart Institute11, Jewish General Hospital12, McGill University13
TL;DR: A brief 4-item scale encompassing lower-extremity weakness, cognitive impairment, anemia, and hypoalbuminemia outperformed other frailty scales and is recommended for use in this setting.
509 citations
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TL;DR: On May 24-25, 2002, a symposium was held at McGill University in Montreal, Quebec, Canada, during which scientists and expert clinicians presented 75 papers on the efficacy of overdentures for the treatment of edentulous patients.
Abstract: On May 24-25, 2002, a symposium was held at McGill University in Montreal, Quebec, Canada, during which scientists and expert clinicians presented 75 papers on the efficacy of overdentures for the treatment of edentulous patients. Strong emphasis was given to evidence from randomized controlled trials in which mandibular two-implant overdentures were compared to conventional dentures. A draft consensus statement was circulated to all presenters, as well as to subjects who participated in some of the clinical trials and other edentulous individuals who attended the symposium. The statoment was modified during the meeting in tight of their comments. We hope that the final version of the consensus statement will serve as a guideline for ctinioians and patients, and that it will stimulate discussion within and between professional organizations, heaith authorities, and thirdparty payers.
387 citations
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301 citations
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TL;DR: The considerable growth in the science and application of pulmonary rehabilitation since 2006 adds further support for its efficacy in a wide range of individuals with chronic respiratory disease.
Abstract: Background: Pulmonary rehabilitation is recognized as a core component of the management of individuals with chronic respiratory disease. Since the 2006 American Thoracic Society (ATS)/European Respiratory Society (ERS) Statement on Pulmonary Rehabilitation, there has been considerable growth in our knowledge of its efficacy and scope.
Purpose: The purpose of this Statement is to update the 2006 document, including a new definition of pulmonary rehabilitation and highlighting key concepts and major advances in the field.
Methods: A multidisciplinary committee of experts representing the ATS Pulmonary Rehabilitation Assembly and the ERS Scientific Group 01.02, “Rehabilitation and Chronic Care,” determined the overall scope of this update through group consensus. Focused literature reviews in key topic areas were conducted by committee members with relevant clinical and scientific expertise. The final content of this Statement was agreed on by all members.
Results: An updated definition of pulmonary rehabilitation is proposed. New data are presented on the science and application of pulmonary rehabilitation, including its effectiveness in acutely ill individuals with chronic obstructive pulmonary disease, and in individuals with other chronic respiratory diseases. The important role of pulmonary rehabilitation in chronic disease management is highlighted. In addition, the role of health behavior change in optimizing and maintaining benefits is discussed.
Conclusions: The considerable growth in the science and application of pulmonary rehabilitation since 2006 adds further support for its efficacy in a wide range of individuals with chronic respiratory disease
Read More: http://www.atsjournals.org/doi/abs/10.1164/rccm.201309-1634ST
2,734 citations
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TL;DR: Findings show that in the context of a dietary pattern that includes high fat consumption, BCAA contributes to development of obesity-associated insulin resistance.
2,611 citations
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2,428 citations
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TL;DR: Dietary supplementation with one or a mixture of these functional AA, which include arginine, cysteine, glutamine, leucine, proline, and tryptophan, may be beneficial for ameliorating health problems at various stages of the life cycle and optimizing efficiency of metabolic transformations to enhance muscle growth, milk production, egg and meat quality and athletic performance.
Abstract: Recent years have witnessed the discovery that amino acids (AA) are not only cell signaling molecules but are also regulators of gene expression and the protein phosphorylation cascade. Additionally, AA are key precursors for syntheses of hormones and low-molecular weight nitrogenous substances with each having enormous biological importance. Physiological concentrations of AA and their metabolites (e.g., nitric oxide, polyamines, glutathione, taurine, thyroid hormones, and serotonin) are required for the functions. However, elevated levels of AA and their products (e.g., ammonia, homocysteine, and asymmetric dimethylarginine) are pathogenic factors for neurological disorders, oxidative stress, and cardiovascular disease. Thus, an optimal balance among AA in the diet and circulation is crucial for whole body homeostasis. There is growing recognition that besides their role as building blocks of proteins and polypeptides, some AA regulate key metabolic pathways that are necessary for maintenance, growth, reproduction, and immunity. They are called functional AA, which include arginine, cysteine, glutamine, leucine, proline, and tryptophan. Dietary supplementation with one or a mixture of these AA may be beneficial for (1) ameliorating health problems at various stages of the life cycle (e.g., fetal growth restriction, neonatal morbidity and mortality, weaning-associated intestinal dysfunction and wasting syndrome, obesity, diabetes, cardiovascular disease, the metabolic syndrome, and infertility); (2) optimizing efficiency of metabolic transformations to enhance muscle growth, milk production, egg and meat quality and athletic performance, while preventing excess fat deposition and reducing adiposity. Thus, AA have important functions in both nutrition and health.
2,047 citations
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TL;DR: This position statement provides evidence-based recommendations and interventions for diabetes MNT and focuses on key references published since the year 2000, and uses grading according to the level of evidence available.
Abstract: Medical nutrition therapy (MNT) is important in preventing diabetes, managing existing diabetes, and preventing, or at least slowing, the rate of development of diabetes complications. It is, therefore, important at all levels of diabetes prevention. MNT is also an integral component of diabetes self-management education (or training). This position statement provides evidence-based recommendations and interventions for diabetes MNT. The previous position statement with accompanying technical review was published in 2002 and modified slightly in 2004. This statement updates previous position statements, focuses on key references published since the year 2000, and uses grading according to the level of evidence available...
1,786 citations