J
José Carlos Miranda
Researcher at Oswaldo Cruz Foundation
Publications - 49
Citations - 1970
José Carlos Miranda is an academic researcher from Oswaldo Cruz Foundation. The author has contributed to research in topics: Leishmania & Saliva. The author has an hindex of 24, co-authored 47 publications receiving 1847 citations. Previous affiliations of José Carlos Miranda include Federal University of Bahia.
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Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model.
Regis Gomes,Regis Gomes,Clarissa Teixeira,Clarissa Teixeira,Maria Jânia Teixeira,Fabiano Oliveira,Fabiano Oliveira,Maria José Menezes,Claire Crola da Silva,Camila I. de Oliveira,José Carlos Miranda,Dia-Eldin A. Elnaiem,Shaden Kamhawi,Jesus G. Valenzuela,Cláudia Brodskyn +14 more
TL;DR: It is shown that immunity to a defined salivary protein (LJM19) confers powerful protection against the fatal outcome of a parasitic disease, which reinforces the concept of using components of arthropod saliva in vaccine strategies against vector-borne diseases.
Journal ArticleDOI
Comparison of the polymerase chain reaction and serology for the detection of canine visceral leishmaniasis.
D A Ashford,Marcelo T. Bozza,M Freire,José Carlos Miranda,Ítalo Rodrigues de Araújo Sherlock,C Eulalio,Ulisses Gazos Lopes,Octavio Fernandes,Wim Degrave,Barker Rh +9 more
TL;DR: The polymerase chain reaction (PCR) and serology was evaluated for the diagnosis of canine visceral leishmaniasis in Bahia, Brazil and it is suggested that the PCR might serve as a better gold standard to define Leishmania infection than culture or hamster inoculation.
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Seroconversion against Lutzomyia longipalpis Saliva Concurrent with the Development of Anti–Leishmania chagasi Delayed-Type Hypersensitivity
Regis Gomes,Cláudia Brodskyn,Cláudia Brodskyn,Camila I. de Oliveira,Jackson Maurício Lopes Costa,José Carlos Miranda,Arlene de Jesus Mendes Caldas,Arlene de Jesus Mendes Caldas,Jesus G. Valenzuela,Manoel Barral-Netto,Aldina Barral +10 more
TL;DR: This simultaneous appearance of anti-saliva humoral response and anti-L.
Journal ArticleDOI
Enhanced Leishmania braziliensis Infection Following Pre-Exposure to Sandfly Saliva
Tatiana Rodrigues de Moura,Fabiano Oliveira,Fabiano Oliveira,Fernanda O. Novais,José Carlos Miranda,Jorge Clarêncio,Ivonise Follador,Edgar M. Carvalho,Jesus G. Valenzuela,Manoel Barral-Netto,Manoel Barral-Netto,Aldina Barral,Aldina Barral,Cláudia Brodskyn,Cláudia Brodskyn,Camila I. de Oliveira +15 more
TL;DR: Pre-exposure to sand fly saliva plays an important role in the outcome of cutaneous leishmaniasis, in both mice and humans, and the need to identify and select the individual salivary candidates instead of using wholesalivary mixture that may favor a non-protective response is emphasized.
Journal ArticleDOI
Frequency of Infection of Lutzomyia Phlebotomines with Leishmania braziliensis in a Brazilian Endemic Area as Assessed by Pinpoint Capture and Polymerase Chain Reaction
José Carlos Miranda,Eliana A. G. Reis,Albert Schriefer,Marilda Souza Goncalves,Mitermayer G. Reis,Lucas P. Carvalho,Octavio Fernandes,Manoel Barral-Netto,Aldina Barral +8 more
TL;DR: The results show that there is a non-homogeneous distribution of Leishmania-infected vectors, and such a clustering may have implications in control strategies against leishmaniasis, and reinforces the necessity of understanding the ecological and geographical factors involved inLeishmanial transmission.