José Miguel Sánchez Márquez

Bio: José Miguel Sánchez Márquez is an academic researcher from Hospital Universitario La Paz. The author has contributed to research in topics: Scoliosis & Vertebra. The author has an hindex of 4, co-authored 5 publications receiving 52 citations.

Proximal junctional vertebral fracture-subluxation after adult spine deformity surgery. Does vertebral augmentation avoid this complication? A case report.

Abstract: Background To report to the orthopedic community a case of vertebral fracture and adjacent vertebral subluxation through the upper instrumented vertebra after thoracolumbar fusion with augmentation of the cranial level.

Decision Making of Graduation in Patients With Early-Onset Scoliosis at the End of Distraction-Based Programs: Risks and Benefits of Definitive Fusion

Abstract: Retrospective comparative analysis. Study early-onset scoliosis (EOS) graduated patients to establish founded criteria for graduation decision making and determine the risks and benefits of definitive fusion. EOS is treated by growth-friendly techniques until skeletal maturity. Afterwards, patients can be “graduated,” either by definitive fusion (posterior spinal fusion [PSF]) or by retaining the previous implants (Observation) with no additional surgery. Criteria for this decision making and the outcomes of definitive fusion are still underexplored. We analyzed a consecutive cohort of “graduated” patients after a distraction-based lengthening program. We gathered demographic, radiographic, and surgical data. The results of the two final treatment options were compared after 2 years’ follow-up. A total of 32 patients were included. Four patients had incomplete records. Thirteen underwent PSF, and 15 were observed. The mean age at initial treatment was 8 ± 3 years, with a mean follow-up of 8.3 ± 2.9 years. Both groups had similar preoperative and final radiographic parameters (p > .05). The criteria for undergoing PSF were as follows: implant-related complications, main curve magnitude (PSF = 63.2° ± 9° vs. OBS = 47.9° ± 15°; p = .008), curve progression >10°, and sagittal misalignment (SVA). During PSF 12/13 patients underwent multiple osteotomies, one vertebrectomy, and 3 costoplasties. Surgical time was 291.5 ± 58 minutes; blood loss was 946 ± 375 mL; and the number of levels fused was 13.7. Coronal deformity was corrected 31%, T1–S1 length gained was 31 ± 19.6 mm and T1–T12 length gained was 9.3 ± 39 mm; kyphosis was reduced by 22%. However, coronal balance worsened by 2.3 ± 30.8 mm. No major complications were encountered in these patients. Graduation by PSF depended on unacceptable or progressive major curve deformity, sagittal misalignment, or complications with previous implants. Observation depended on curve stabilization, Cobb <50°, and coronal misalignment <20 mm. Definitive fusion effectively corrected coronal and sagittal deformity and increased trunk height. However, it exposed patients to a very demanding surgery without improvement in coronal balance. Level III, therapeutic.

Case Reports: Tantalum Debris Dispersion During Revision of a Tibial Component for TKA

Abstract: Porous tantalum nonmodular tibial components for TKA were introduced in 1999. We revised three well-fixed tantalum tibial trays. For removal, we used osteotomes and revision oscillating saw blades. Removal of the components was laborious and resulted in generation of abundant tantalum debris that seeded the periarticular soft tissues despite meticulous protection with gauze. The retained metallic debris that is visible on postoperative radiographs has the potential for generation of third-body wear. We alert the orthopaedic community about this phenomenon and recommend minimizing the use of motorized revision instruments for removal of trabecular metal implants.

Gradual scoliosis correction over time with shape-memory metal: a preliminary report of an experimental study

Abstract: Background Severe and progressive scoliosis is a complex threedimensional spinal deformity that commonly requires treatment to address curve progression during growth. Standard treatment options for progressive scoliosis are essentially limited to bracing or surgery. Brace treatment is noninvasive and preserves growth; however it is only modestly successful in preventing curve progression and has a negative psychological impact [1-3] that may decrease patient compliance. Instead, surgical treatment with an instrumented spinal arthrodesis usually results in good deformity correction but has several risks. Those risks are associated to the invasiveness of spinal arthrodesis, the instantaneous correction of spinal deformity, and the altered biomechanics of the fused spine. Spinal fusion can have deleterious effects on subsequent development. Besides the known loss of motion and risk of adjacent segment disease with long-segment fusion, the loss of growth potential can lead to a significant decrease in trunk height and may negatively impact pulmonary development. Therefore, recent interest has been focused on new strategies for the effective surgical management of severe scoliosis in young children without the use of multisegmental spinal fusion. Fusionless scoliosis surgery provides theoretical advantages over traditional surgical arthrodesis, including the potential preservation of growth, motion and function of the spine [4]. In this way, several methods have been developed to treat scoliosis in young patients that allow the natural growth and elongation of the developing spine.

Proximal junctional kyphosis and failure after spinal deformity surgery: a systematic review of the literature as a background to classification development.

Abstract: Study design Systematic review of literature. Objective To perform a comprehensive English language systematic literature review of proximal junctional kyphosis (PJK) and proximal junctional failure (PJF), concentrating on incidence, risk factors, health related quality of life impact, prevention strategy, and classification systems. Summary of background data PJK and PJF are well described clinical pathologies and are a frequent cause of revision surgery. The development of a PJK classification that correlates with clinical outcomes and guides treatment decisions and possible prevention strategies would be of significant benefit to patients and surgeons. Methods The phrases "proximal junctional," "proximal junctional kyphosis," and "proximal junctional failure" were used as search terms in PubMed for all years up to 2014 to identify all articles that included at least one of these terms. Results Fifty-three articles were identified overall. Eighteen articles assessed for risk factors. Eight studies specifically reviewed prevention strategies. There were no randomized prospective studies. There were 3 published studies that have attempted to classify PJK. The reported incidence of PJK ranged widely, from 5% to 46% in patients undergoing spinal instrumentation and fusion for adult spinal deformity. It is reported that 66% of PJK occurs within 3 months and 80% within 18 months after surgery. The reported revision rates due to PJK range from 13% to 55%. Modifiable and nonmodifiable risk factors for PJK have been characterized. Conclusion PJK and PJF affect many patients after long segment instrumentation after the correction of adult spinal deformity. The epidemiology and risk factors for the disease are well defined. A PJK and PJF scoring system may help describe the severity of disease and guide the need for revision surgery. The development and prospective validation of a PJK classification system is important considering the prevalence of the problem and its clinical and economic impact. Level of evidence N/A.

Junctional spinal disorders in operated adult spinal deformities: present understanding and future perspectives

Abstract: Introduction Junctional spinal disorders have become one of the greatest challenges in spinal deformity surgery. They can occur at any age but are mostly seen in adult deformity surgery and are most often observed as the patient gets older.

Proximal junctional kyphosis and failure—diagnosis, prevention, and treatment

Abstract: Technical advancements have enabled the spinal deformity surgeon to correct severe spinal mal-alignment. However, proximal adjacent segment pathology (ASP) remains a significant issue. Examples include proximal junctional kyphosis (PJK) and proximal junctional failure (PJF). Agreement on the definition, classification, and pathophysiology of PJK and PJF remains incomplete, and an understanding of the risk factors, means of prevention, and treatment of this problem remains to be elucidated. In general, PJK is a relatively asymptomatic radiographic diagnosis managed with patient reassurance and monitoring. On the other hand, PJF is characterized by mechanical instability, pain, and more severe kyphosis, with potential for neurologic compromise. Patients who develop PJF more often require revision surgery than those with PJK. This chapter will review the current understanding of PJK and PJF.

Proximal Junctional Kyphosis: Diagnosis, Pathogenesis, and Treatment.

Abstract: Proximal junctional kyphosis (PJK) is a common radiographic finding after long spinal fusion. A number of studies on the causes, risk factors, prevention, and treatment of PJK have been conducted. However, no clear definition of PJK has been established. In this paper, we aimed to clarify the diagnosis, prevention, and treatment of PJK by reviewing relevant papers that have been published to date. A literature search was conducted on PubMed using "proximal junctional", "proximal junctional kyphosis", and "proximal junctional failure" as search keywords. Only studies that were published in English were included in this study. The incidence of PJK ranges from 5% to 46%, and it has been reported that 66% of cases occur 3 months after surgery and approximately 80% occur within 18 months. A number of studies have reported that there is no significantly different clinical outcome between PJK patients and non-PJK patients. One study showed that PJK patients expressed more pain than non-PJK patients. However, recent studies focused on proximal junctional failure (PJF), which is accepted as a severe form of PJK. PJF showed significant adverse impact in clinical aspect such as pain, neurologic deficit, ambulatory difficulties, and social isolation. Numerous previous studies have identified various risk factors and reported on the treatment and prevention of PJK. Based on these studies, we determined the clinical significance and impact of PJK. In addition, it is important to find a strategic approach to the proper treatment of PJK.