J
Josep Dalmau
Researcher at Catalan Institution for Research and Advanced Studies
Publications - 599
Citations - 58338
Josep Dalmau is an academic researcher from Catalan Institution for Research and Advanced Studies. The author has contributed to research in topics: Encephalitis & Limbic encephalitis. The author has an hindex of 108, co-authored 568 publications receiving 49331 citations. Previous affiliations of Josep Dalmau include New York University & Boston Children's Hospital.
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Journal ArticleDOI
Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies
Josep Dalmau,Amy J. Gleichman,Ethan G. Hughes,Jeffrey E. Rossi,Xiaoyu Peng,Meizan Lai,Scott K. Dessain,Myrna R. Rosenfeld,Rita J. Balice-Gordon,David A. Lynch,David A. Lynch +10 more
TL;DR: A well-defined set of clinical characteristics are associated with anti-NMDA-receptor encephalitis and the pathogenesis of the disorder seems to be mediated by antibodies.
Journal ArticleDOI
Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study
Maarten J. Titulaer,Lindsey McCracken,Iñigo Gabilondo,Thaís Armangue,Carol A. Glaser,Takahiro Iizuka,Lawrence S. Honig,Susanne M. Benseler,Izumi Kawachi,Eugenia Martinez-Hernandez,Eugenia Martinez-Hernandez,Esther Aguilar,Nuria Gresa-Arribas,Nicole Ryan-Florance,Abiguei Torrents,Albert Saiz,Myrna R. Rosenfeld,Myrna R. Rosenfeld,Rita J. Balice-Gordon,Francesc Graus,Josep Dalmau,Josep Dalmau,Josep Dalmau +22 more
TL;DR: Most patients with anti-NMDAR encephalitis respond to immunotherapy; second-line immunotherapy is usually effective when first-line treatments fail, and outcomes continued to improve for up to 18 months after symptom onset.
Journal ArticleDOI
Paraneoplastic anti–N‐methyl‐D‐aspartate receptor encephalitis associated with ovarian teratoma
Josep Dalmau,Erdem Tüzün,Hai-Yan Wu,Jaime Masjuan,Jeffrey E. Rossi,Alfredo Voloschin,Joachim M. Baehring,Haruo Shimazaki,Reiji Koide,Dale King,Warren P. Mason,Lauren H Sansing,Marc A. Dichter,Myrna R. Rosenfeld,David A. Lynch +14 more
TL;DR: The autoantigens of a new category of treatment‐responsive paraneoplastic encephalitis are reported, and it is proposed that this category should be combined with existing treatment-responsive encephalopathy categories.
Journal ArticleDOI
Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis
Josep Dalmau,Eric Lancaster,Eugenia Martinez-Hernandez,Myrna R. Rosenfeld,Rita J. Balice-Gordon +4 more
TL;DR: Patients' antibodies cause a titre-dependent, reversible decrease of synaptic NMDAR by a mechanism of crosslinking and internalisation, which reveals a probable pathogenic relation between the depletion of receptors and the clinical features of anti-NMDAR encephalitis.
Journal ArticleDOI
Recommended diagnostic criteria for paraneoplastic neurological syndromes
Francesc Graus,Jean Yves Delattre,Jean-Christophe Antoine,Josep Dalmau,Bruno Giometto,Wolfgang Grisold,J. Honnorat,P. A. E. Sillevis Smitt,Ch Vedeler,Jan J.G.M. Verschuuren,Angela Vincent,Raymond Voltz +11 more
TL;DR: An international panel of neurologists interested in PNS recommended new criteria for those in whom no clinical consensus was reached in the past and defined “classical” syndrome and onconeural antibody as “well characterised”.