J
Joseph H. Callicott
Researcher at National Institutes of Health
Publications - 116
Citations - 25498
Joseph H. Callicott is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Prefrontal cortex & Working memory. The author has an hindex of 67, co-authored 116 publications receiving 24418 citations. Previous affiliations of Joseph H. Callicott include University of Texas Health Science Center at Houston & United States Department of Health and Human Services.
Papers
More filters
Journal ArticleDOI
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
Michael F. Egan,Masami Kojima,Masami Kojima,Joseph H. Callicott,Terry E. Goldberg,Bhaskar Kolachana,Alessandro Bertolino,Eugene Zaitsev,Bert Gold,David Goldman,Michael Dean,Bai Lu,Daniel R. Weinberger +12 more
TL;DR: A role is demonstrated for BDNF and its val/met polymorphism in human memory and hippocampal function and it is suggested val/ met exerts these effects by impacting intracellular trafficking and activity-dependent secretion of BDNF.
Journal ArticleDOI
Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia.
Michael F. Egan,Terry E. Goldberg,Bhaskar Kolachana,Joseph H. Callicott,C.M. Mazzanti,Richard E. Straub,David Goldman,Daniel R. Weinberger +7 more
TL;DR: The data suggest that the COMT Val allele, because it increases prefrontal dopamine catabolism, impairs prefrontal cognition and physiology, and by this mechanism slightly increases risk for schizophrenia.
Journal ArticleDOI
Brain-Derived Neurotrophic Factor val66met Polymorphism Affects Human Memory-Related Hippocampal Activity and Predicts Memory Performance
Ahmad R. Hariri,Terry E. Goldberg,Venkata S. Mattay,B Kolachana,Joseph H. Callicott,Michael F. Egan,Daniel R. Weinberger +6 more
TL;DR: The relationship of the BDNF val66met genotype and hippocampal activity during episodic memory processing using blood oxygenation level-dependent functional magnetic resonance imaging and a declarative memory task in healthy individuals suggests that the basic effects of BDNF signaling on hippocampal function in experimental animals are important in humans.
Journal ArticleDOI
Catechol O-methyltransferase val158-met genotype and individual variation in the brain response to amphetamine.
Venkata S. Mattay,Terry E. Goldberg,Francesco Fera,Ahmad R. Hariri,Alessandro Tessitore,Michael F. Egan,Bhaskar Kolachana,Joseph H. Callicott,Daniel R. Weinberger +8 more
TL;DR: Basic evidence of an inverted-“U” functional-response curve to increasing dopamine signaling in the prefrontal cortex is extended and individuals with the met/met catechol O-methyltransferase genotype appear to be at increased risk for an adverse response to amphetamine.
Journal ArticleDOI
The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology
Lukas Pezawas,Beth A. Verchinski,Venkata S. Mattay,Joseph H. Callicott,Bhaskar Kolachana,Richard E. Straub,Michael F. Egan,Andreas Meyer-Lindenberg,Daniel R. Weinberger +8 more
TL;DR: It is shown that, in magnetic resonance imaging scans of a large sample of normal individuals, this polymorphism affects the anatomy of the hippocampus and prefrontal cortex, identifying a genetic mechanism of variation in brain morphology related to learning and memory.