Joseph J. Vitti

TL;DR: The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations, and has reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-generation sequencing, deep exome sequencing, and dense microarray genotyping.

TL;DR: The 1000 Genomes Project as mentioned in this paper provided a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations, and reported the completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole genome sequencing, deep exome sequencing and dense microarray genotyping.

TL;DR: A comprehensive outline of evolutionary genomics methods is provided, highlighting the importance of functional follow-up studies to characterize putative selected alleles and the use of selection scans as hypothesis-generating tools for investigating evolutionary histories.

TL;DR: In this paper, a genomic catalog of almost 200 Lassa virus (LASV) sequences from clinical and rodent reservoir samples was generated, showing that whereas the 2013-2015 West African epidemic of Ebola virus disease (EVD) was fueled by human-to-human transmissions, LASV infections mainly result from reservoir-tohuman infections.

TL;DR: iSAFE (for “integrated selection of allele favored by evolution”), a method that enables researchers to accurately pinpoint the favored mutation in a large region by using a statistic derived solely from population genetics signals.