J
Joseph O. Deasy
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 461
Citations - 20302
Joseph O. Deasy is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Radiation therapy & Cancer. The author has an hindex of 61, co-authored 418 publications receiving 17183 citations. Previous affiliations of Joseph O. Deasy include University of Louisville & Aarhus University.
Papers
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Journal ArticleDOI
Use of normal tissue complication probability models in the clinic.
Lawrence B. Marks,Ellen Yorke,Andrew Jackson,Randall K. Ten Haken,Louis S. Constine,Avraham Eisbruch,Søren M. Bentzen,Jiho Nam,Joseph O. Deasy +8 more
TL;DR: The Quantitative Analysis of Normal Tissue Effects in the Clinic (QUANTEC) review summarizes the currently available three-dimensional dose/volume/outcome data to update and refine the normal tissue dose/ volume tolerance guidelines provided by the classic Emami et al. paper published in 1991.
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Tomotherapy: A new concept for the delivery of dynamic conformal radiotherapy
T. Rock Mackie,Timothy Holmes,Stuart Swerdloff,Paul J. Reckwerdt,Joseph O. Deasy,James N. Yang,Bhudatt R. Paliwal,Timothy J. Kinsella +7 more
TL;DR: Tomotherapy, literally "slice therapy," is a proposal for the delivery of radiation therapy with intensity-modulated strips of radiation, which employs a linear accelerator, or another radiation-emitting device, which would be mounted on a ring gantry like a CT scanner.
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Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC): An Introduction to the Scientific Issues
Søren M. Bentzen,Louis S. Constine,Joseph O. Deasy,A. Eisbruch,Andrew Jackson,Lawrence B. Marks,Randall K. Ten Haken,Ellen Yorke +7 more
TL;DR: Clinical limitations to the current knowledge base include the need for more data on the effect of patient-related cofactors, interactions between dose distribution and cytotoxic or molecular targeted agents, and theeffect of dose fractions and overall treatment time in relation to nonuniform dose distributions.
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Radiation dose-volume effects in the lung.
Lawrence B. Marks,Søren M. Bentzen,Joseph O. Deasy,Feng-Ming Spring Kong,Jeffrey D. Bradley,I. Vogelius,Issam El Naqa,Jessica L. Hubbs,Joos V. Lebesque,Robert Timmerman,Mary K. Martel,Andrew Jackson +11 more
TL;DR: The three-dimensional dose, volume, and outcome data for lung are reviewed in detail and it is confirmed that there is no evident threshold "tolerance dose-volume" levels and there are strong volume and fractionation effects.
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CERR: A computational environment for radiotherapy research
TL;DR: CERR provides a powerful, convenient, and common framework which allows researchers to use common patient data sets, and compare and share research results.