Joseph Thomas Velardo

Bio: Joseph Thomas Velardo is an academic researcher. The author has contributed to research in topics: Infertility. The author has an hindex of 4, co-authored 4 publications receiving 591 citations.

Histochemistry, Theoretical and Applied.

Abstract: municable disease control to the newer responsibilities of the hazards of ionizing radiation and medical defense against atomic attack. The individual topics are adequately developed with emphasis, in the majority, on brevity of presentation rather than complete and exhaustive detail. References are listed after each chapter for the reader desiring more definitive information. \"Epidemiologic Methods and Inferences\" by Dr. Dienfeld and \"Official and Voluntary Health Agencies\" by Dr. Hilleboe are two chapters which offer especially well-organized, succinct, and effective discussions of their respective subjects. The editors state in their preface that they are presenting \". . a new way to look at preventive medicine for the medical students, general practitioners, specialists, and professional workers in official and voluntary health agencies.\" In the opinion of the reviewer, the authors have achieved their purpose by editing a book which is more an introductory text than a reference tome.

A Textbook of General Physiology

Abstract: troversy where it properly belonged. In his uni-directional approach to the origin of cells, and in other areas as well, it was obvious that the data included, and the interpretation, depended on \"hindsight.\" He may also be criticised for overlooking his principles of the scientific method (admirably presented in an earlier section) by appending finality to a body of selected data. In other instances where information is either lacking or opinions are severely divided the \"conspicuous-by-absence\" fault must apply. In discussions of high-energy phosphate sources in the citric acid cycle or mechanisms of protein synthesis, for example, a few qualifications to the student would seem advisable, especially since such problems are fundamental to life and considerable space had been devoted to them. Hence, the reviewer would have proferred to see some of the unknown elements of science presented in proper perspective, which the talents of the author would permit him to do. Were it not for the question marks between the periods there would be no scientists, and even for thoughtful students, finality in the method of presentation dispels intrigue. In the second edition of this remarkable and highly successful textbook of general physiology, Professor Davson performs a commendable task in presenting a most lucid account of the principles of physiology. The success of the present work is primarily due to his ability to be both clear and concise. He defines general physiology as the study of those features that appear to be common to all forms. Davson's new work is divided into six sections: Organism. The section on neurophysiology is very interestingly developed and is certainly a step forward in the beautiful integration of neuroanatomy (including cytology), neurophysiology, and neuropharmacology. This new and revised textbook, which is considerably larger than its predecessor, will appeal to a wide and divergent community of scholars. First and foremost, it is oriented for the advanced student of physiology, both general and comparative. Secondly, it presents an enormous amount of highly specific and accurately detailed data for students of medical physiology. Finally, the research worker in physiology will realize much profit by arming himself with an authoritative analysis of the latest concepts of physiology described. The author presents an up-to-date account of the principles of general physiology and in doing so makes liberal use of current references. Of singular significance is his evaluation of the current references cited in his new edition. Giving added …

Reproduction and Infertility III Symposium

Abstract: sumption that libido is basically pleasure-seeking, and proposes instead Fairbairn's view that it seeks contact with objects: for example, the infant's mouth becomes erotized because it is the route toward, or the bodily structure for, contacting the libidinally desired object (the breast). Stanton, in discussing object choice, would add knowledge of social and group behavior theory to the traditional conceptions of object choice (which see it as an expression of identification, anaclitic relationship, or libidinal satisfaction); he points out that current theory is not very helpful in understanding the object relationships in the mature mutuality of love. Few of the thoughts reported here pass unchallenged in this symposium, and there are spirited disagreements if not diametrically opposed points of view reported, all of which makes not only interesting reading but lends conviction to the premise of the conference that there is still unresolved difference of interpretation and inadequacy of definition in many of the important constructs of psychoanalytic theory. For the reader with adequate background , it makes stimulating reading. Reproduction and Infertility III Symnposiumn represents the edited proceedings of the third in a series of biennial symposia sponsored by various colleges of veterinary medicine. This nicely organized composite of facts on reproductive physiology is divided into five sections: diseases of reproduction in the male and female, ovarian physiology, steroid physiology and therapy, general problems of reproduction, and semen metabolism. Discussions of the twenty formal papers covering these broad areas as well as a round table seminar on artificial insemination and frozen semen are included, Hill. Except for two papers dealing with human subjects, the emphasis is entirely on animal husbandry. The paper by Nowakowski on human male hypogonadism is particularly noteworthy. Though much of the subject matter has no direct application to the human, many of the more basic concepts, particularly in the field of ovarian physiology and sperm metabolism, may serve as a guide for studies along similar lines on human material. For this reason, the symposium, which is certainly of value to those interested in animal husbandry, should be useful to workers in human reproductive physiology as well.

Reproductive Physiology. Comparative Reproductive Physiology of Domestic Animals, Laboratory Animals and Man.

Abstract: in middle ear surgery. Concurrent improvements in the operating microscope made it possible to visualize middle ear structures in amazingly clear detail, and revealed to the ear surgeon the possibilities of preserving or restoring hearing in the surgical treatment of chronic middle ear infections. Since 1952 many articles have appeared describing various techniques of reconstructive surgery of the sound-conducting apparatus, and a few others have discussed the physiological principles on which these procedures are based. The present work serves an important need in providing the otologic surgeon with a thoroughgoing analysis of the technical and physiological aspects of middle ear surgery in one comprehensive volume. It describes in detail the experimental methods used in investigating middle ear function in the laboratory. A brief review of the pathology and physiology of the middle ear is included and there is a concise presentation of acoustic physics in understandable language. Finally, a clear, well-written section on treatment covers the newest techniques in the surgery of middle ear deafness. These include stapes mobilization, fenestration, prosthesis and tympanoplasty, each section written by a leading authority in the field. The reader might regret that nonsurgical methods of treating and preventing middle ear disease and deafness are not included. The average otolaryngologist consulting a volume by this title might expect to find a section on middle ear effusion since it is a frequent cause of conductive deafness and often requires surgical treatment. These topics are apparently outside the scope of this volume. The sections on testing and on pathology are rather sketchy but the otologic surgeon looking for a well-written, clearly illustrated description of the newest techniques in microsurgery of the middle ear will find this book a valuable source of information.

The yo-yo intermittent recovery test: physiological response, reliability, and validity.

Abstract: KRUSTRUP, P, M MOHR, T AMSTRUP, T RYSGAARD, J JOHANSEN, A STEENSBERG, P K PEDERSEN, and J BANGSBO The Yo-Yo Intermittent Recovery Test: Physiological Response, Reliability, and Validity Med Sci Sports Exerc, Vol 35, No 4, pp 697–705, 2003PurposeTo examine the physiological

Retinal damage by light in rats

Abstract: The retina of laboratory rats is affected irreversibly by intense light applied for less than 1 hour or for up to 2 days depending upon experimental conditions. Exposure of unanesthetized and unrestrained animals was in chambers surrounded by a green filter and circular fluorescent lamps of a nominal brightness of 2,040 footlamberts. Eyes of anesthetized animals were exposed diffusely to either the light from a 100 to. zirconium arc passing through filters or monochromatic light of various icavelengths. Irreversible reduction in ERG amplitudes and degeneration of visual cells and pigment epithelium indicated the severity of the light damage. The effect was very dependent upon the body (eye) temperature during exposure. Hyperthermia greatly accelerated and intensified the damaging action of light and for this reason most experiments reported in this paper were performed at a high body temperature. At a body temperature around 104° F. severe damage teas produced with exposures to 5 to 10 iiw per square centimeter retina for 1 hour. The minimal damaging dose at a high temperature was estimated to be about 1 ixw per square centimeter. The action spectrum~of the daviaging effect approximated that of visual excitation as measured by the ERG. Hooded (pigmented) animals were no more affected than albinos of different strains. Recovery in the dark from a just subliminally damaging dose of light at a high body temperature required about 24 hours and was preceded by a period of time during ichich the retina was "sensitized" to an additional dose. During or following exposure to light at a high body temperature visual cell and pigmentepithelial_damage developedTabout simultaneouslu and was first indicated bit pyknosis Trncl cell swelling followed rapidly by the dissolution of nuclei and cytoplasm. The crucial reaction in producing the damage is considered a "dark-reaction" initiated by light of an -inte7isiiTj_ which bleaches measurably rhodopsin. Hypotheses on the reaction sequence which 'leads to damage are briefly discussed.

New cytoplasmic components in arterial endothelia.

Abstract: A hitherto unknown rod-shaped cytoplasmic component which consists of a bundle of fine tubules, enveloped by a tightly fitted membrane, was regularly found in endothelial cells of small arteries in various organs in rat and man. It is about 0.1 µ thick, measures up to 3 µ in length, and contains several small tubules, ∼150 A thick, embedded in a dense matrix, and disposed parallel to the long axis of the rod. In some of these cells, the cisternae of the endoplasmic reticulum are greatly distended by the accumulation of a dense, finely granular material. The nature and significance of these cytoplasmic components are yet unknown.

Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

Abstract: Swelling of primary astrocyte cultures by exposing them to hypotonic media caused release of label after the cells had been allowed to accumulate 3H-L-glutamate, 3H-D-aspartate, or 3H-taurine. Comparable release of endogenous L-glutamate or taurine, as measured by high- pressure liquid chromatography (HPLC), was also found. Release of label was not affected by treating the cells with cytochalasin B, indicating that microfilament polymerization was not significantly involved. Hypotonic-induced release did not appear to principally involve reversal of the Na(+)-dependent uptake system since increasing external K+ to depolarize the cells by replacement of external Na+, thus maintaining isotonic conditions, increased release to a lesser extent. Threo beta-hydroxyaspartate, a potent 3H-L-glutamate uptake blocker, added externally stimulated efflux of 3H-L-glutamate independently of the swelling-induced efflux. Upon restoration of swollen cells to isotonic medium they showed an unimpaired ability to take up 3H-L- glutamate. The swelling-induced release of label was inhibited by a number of anion transport inhibitors, one of which has been shown to significantly improve outcome in an experimental brain trauma/hypoxia model in which astrocyte swelling is an early event.