Synthetic Analogues and Reaction Systems Relevant to the Molybdenum and Tungsten Oxotransferases

Coordination compounds of copper, nickel and iron with Schiff bases derived from hydroxynaphthaldehydes and salicylaldehydes

The biologically relevant oxygen atom transfer chemistry of molybdenum: from synthetic analogue systems to enzymes

Publisher Summary This chapter presents a discussion on the bioinorganic chemistry of pterin-containing molybdenum and tungsten enzymes. The chapter focuses on the current results and the interplay of model and enzyme chemistry. Attention is directed to sulfite oxidase and xanthine oxidase, the archetypal examples of molybdenum enzymes, containing, respectively, dioxo-Mo(VI) and oxo-thio-Mo(VI) oxidized centers. Biochemical and model studies of molybdopterin, Mo-co, and related species are described in this chapter. A brief survey on the physical and spectroscopic techniques employed in the study of the enzymes is presented and their impact on the current understanding of the coordination about the molybdenum atom in sulfite oxidase and xanthine oxidase is discussed. Structural and spectroscopic models are also presented in the chapter. The chapter also explains the xanthine oxidase cycle and facets of intramolecular electron transfer in molybdenum enzymes. The pterin-containing tungsten enzymes and the evolving model chemistry are discussed. Current descriptions of the coordination environment of the molybdenum centers of the enzymes rest primarily upon the comparisons of the spectra of the enzymes with the spectra of well-characterized molybdenum complexes. The unexpected discovery that several hyperthermophilic organisms possess pterin-containing tungsten enzymes promises to stimulate the development of oxo-thio-tungsten chemistry.

Bioinorganic chemistry of pterin-containing molybdenum and tungsten enzymes

The nuclear magnetic resonance properties of chromium, molybdenum and tungsten compounds

Etude de 30 a 60°C des reactions de transfert de l'atome O pour MoO 2 L (L=(5X-salicylidene) amino)-2 benzenethiolate ou -ethanethiolate. Parametres d'activation

Ligand control of cis-dioxomolybdenum(VI) redox chemistry: kinetic and activation parameter data for oxygen atom transfer

Synthesis and electrochemistry of cis-dioxomolybdenum(VI) complexes with tridentate Schiff base ligands containing O, N and S donor atoms

Series of cis-dioxo-MoL.DMF complexes have been investigated using FT-IR spectroscopy in DMF solution. The ligands (L) used are obtained from Schiff base condensation of 5-X-salicylaldehyde (X=NO 2 , Br, H, OCH 3 ) with o-aminophenol, o-aminobenzenethiol, 2-aminoethanol, 2-aminoethanethiol, 2-amino-5-nitrophenol or 2-amino-4-nitrophenol

Joseph Topich

Papers

Ligand control of cis-dioxomolybdenum(VI) redox chemistry: kinetic and activation parameter data for oxygen atom transfer

Synthesis and electrochemistry of cis-dioxomolybdenum(VI) complexes with tridentate Schiff base ligands containing O, N and S donor atoms

Solution IR spectroscopic studies of cis-dioxomolybdenum(VI) complexes

Molybdenum-95 NMR spectra of dioxomolybdenum(VI) schiff base complexes

Kinetic study on the reaction of cis-dioxo-(N-(5-X-salicylidene)-2-aminobenzenethiolato) molybdenum(VI) with ethyldiphenylphosphine