Joshua N. Bembenek

TL;DR: A new microscope using ultrathin light sheets derived from two-dimensional optical lattices is developed, demonstrating the performance advantages of lattice light-sheet microscopy compared with previous techniques and highlighted phenomena that, when seen at increased spatiotemporal detail, may hint at previously unknown biological mechanisms.

TL;DR: It is shown that phosphorylation of human Cdh1 (hCdh1) by cyclin B-Cdc2 alters the conformation of hCdh2 and prevents it from activating APC, and hCdc14a may promote the activation of APCCdh1 and exit from mitosis in mammalian cells.

TL;DR: In this paper, the authors identified cortical granules in Caenorhabditis elegans and found that degranulation occurs in a wave that initiates in the vicinity of the meiotic spindle during anaphase I. They concluded that osmotic sensitivity phenotypes occur because of defects in trafficking of cortical granule and subsequent formation of an impermeable eggshell.

TL;DR: It is shown that Cdc14p contains a leucine-rich nuclear export signal (NES) that interacts with Crm1p physically and is involved in coordinating mitotic exit and cytokinesis in budding yeast.

TL;DR: Data indicate that separase is required for cytokinesis by regulating the incorporation of RAB-11-positive vesicles into the plasma membrane at the cleavage furrow and midbody.