Josiane Seydoux

TL;DR: It is shown that to accommodate the increased requirement for hepatic fatty acid oxidation, PPAR α mRNA is induced during fasting in wildtype mice, indicating that PPARα plays a pivotal role in the management of energy stores during fasting.

TL;DR: The novel UCP3 was 57% and 73% identical to human UCP1 and UCP2, respectively, highly skeletal muscle‐specific and its expression was unaffected by cold acclimation, suggesting this new member of the UCP family is a candidate protein for the modulation of the respiratory control in skeletal muscle.

TL;DR: These animal models demonstrate that AGT produced by adipose tissue plays a role in both local adipOSE tissue development and in the endocrine system, which supports a role of adipose AGT in hypertensive obese patients.

TL;DR: It is proposed that the green tea extract is effective in stimulating thermogenesis by relieving inhibition at different control points along the NA–cAMP axis, and a synergistic interaction between catechin-polyphenols and caffeine to augment and prolong sympathetic stimulation of thermogenesis could be of value in assisting the management of obesity.

TL;DR: The results demonstrate the importance of NPY Y1 receptors in NPY-mediated cardiovascular response and in the regulation of body weight through central control of energy expenditure and are also indicative of a role for the Y1 receptor in the control of food intake.