Juan B. Kouri

TL;DR: The results indicate that the bactericidal properties of the nanoparticles are size dependent, since the only nanoparticles that present a direct interaction with the bacteria preferentially have a diameter of approximately 1-10 nm.

TL;DR: The term ‘chondroptosis’ is proposed to reflect the fact that such cells are undergoing apoptosis in a non-classical manner that appears to be typical of programmed chondrocyte death in vivo, and it is speculated that the endoplasmic reticulum pathway of apoptosis plays a greater role than receptor-mediated or mitochondrial pathways and that lysosomal proteases are at least as important as caspases.

TL;DR: Evaluating apoptosis and autophagy using Immunohistochemistry and Western blot techniques in an animal OA model indicates a combination of both death processes.

TL;DR: The absence of mitotic figures and the presence of motile elements in many chondrocytes raise the possibility that cell aggregates or "clones' in damaged OA cartilage originate by an active process of cell migration rather than by cellular division.

TL;DR: Several microscopical techniques were used in a correlative morphological study of human osteoarthritic (OA) cartilage, and emphasis was made on the characterization of chondrocytes heterogeneity observed in this tissue.