Author
Juan Carlos Samamé-Pérez-Vargas
Bio: Juan Carlos Samamé-Pérez-Vargas is an academic researcher. The author has contributed to research in topics: Epithelioid hemangioendothelioma & Hemangioendothelioma. The author has an hindex of 1, co-authored 1 publications receiving 22 citations.
Papers
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TL;DR: The case of an 85 years old male patient diagnosed of pleural epithelioid hemangioendothelioma, taking advantage to review exhaustively literature and therapy for the disease is reported.
23 citations
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TL;DR: Among 4 different thoracic involvement types, the lung multinodular pattern tended to demonstrate longer median survival than other patterns, whereas the shortest median survival was observed for the nodule/mass with pleural involvement pattern.
27 citations
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TL;DR: The radiologic and pathologic features of the less common primary pleural tumors are described and a diagnostic approach to their evaluation is proposed.
22 citations
TL;DR: A diagnostically challenging case of HEHE is presented where capecitabine and bevacizumab are utilized as another novel treatment option.
Abstract: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare, often misdiagnosed vascular neoplasm with clinical behaviors that range from indolent to highly aggressive. Even when the appropriate diagnosis is achieved, the best treatment for HEHE has not been defined or standardized, further complicating the care of these patients. We present a diagnostically challenging case of HEHE where we utilized capecitabine and bevacizumab as another novel treatment option.
21 citations
TL;DR: A 71-year-old man with pleural EHE harboring CAMTA1 rearrangement confirmed by fluorescence in situ hybridization on paraffin embedded tissue is reported.
19 citations
TL;DR: Significant challenges in the diagnosis and management of patients with pleural PHE exist, including a wide initial differential diagnosis and difficulties in obtaining tissue specimens, coupled with relatively limited treatment options.
Abstract: Epithelioid hemangioendothelioma (EHE) is a rare malignant cancer of vascular origin that can affect multiple and varied tissue sites. A subtype of EHE, pulmonary epithelioid hemangioendothelioma (PHE), is more unusual with only 200 reported cases. Of these, only 27 have been classified as pleural in origin. Based on available literature, the average age of presentation of pleural PHE is 45.7 years with a male preponderance of 2.375. A summary of all published case reports reveals significant heterogeneity both in presentation and management. Here we add to this knowledge-base with a report of an unusual case of pleural PHE in a 36-year-old female who presented with a 6-week history of chest pain and breathlessness. Significant challenges in the diagnosis and management of patients with pleural PHE exist, including a wide initial differential diagnosis and difficulties in obtaining tissue specimens, coupled with relatively limited treatment options. Early referral to a cardiothoracic center for video-assisted thoracoscopic biopsy is crucial in facilitating a diagnosis and allowing adequate pleural drainage for symptomatic relief. J Clin Med Res. 2015;7(7):566-570 doi: http://dx.doi.org/10.14740/jocmr2174w
18 citations