scispace - formally typeset
Search or ask a question
Author

Juan J. Fiol

Bio: Juan J. Fiol is an academic researcher from University of the Balearic Islands. The author has contributed to research in topics: Ligand & Non-covalent interactions. The author has an hindex of 21, co-authored 69 publications receiving 1307 citations. Previous affiliations of Juan J. Fiol include Spanish National Research Council.


Papers
More filters
Journal ArticleDOI
TL;DR: X-ray crystal structures for two N-salicylidene tryptophanato diaquocopper(II) isomers, [Cu(Sal-Trp)(h2O)2, erythro (1) and hreo (2), were reported in this article.

33 citations

Journal ArticleDOI
TL;DR: In this article, the synthesis in aqueous ethanol solution of eight Zn(II) compounds of salicylaldehyde-amino acid Schiff bases together with their spectral characterisation is reported.

30 citations

Journal ArticleDOI
TL;DR: In this paper, a new chloride-dimethylsulfoxide-ruthenium (III) complex with nicotine trans-[RuIIICl4(DMSO)[H-(Nicotine)]] (1) and three related iridium(III) complexes were synthesized and characterized by spectroscopic techniques and by single crystal X-ray diffraction.

30 citations

Journal ArticleDOI
TL;DR: Two new chloride-dimethylsulfoxide-ruthenium(III) complexes, [RuIIICl4(DMSO)(H-Hypoxanthine)] (1) and as discussed by the authors, have been prepared and structurally characterized by X-ray diffraction crystallography.

30 citations

Journal ArticleDOI
TL;DR: In this article, the authors used 1H and 13C NMR data to identify free acyclovir molecules by Ni(or Co)-ACV (1 and 2).
Abstract: The monomeric [M(ACV)2(H2O)4]Cl2·2ACV (M = NiII 1 or CoII 2), [Zn(ACV)Cl2(H2O)] 3 and the polymeric [Cd(ACV)Cl2]·H2O 4 [ACV = acyclovir = 9-(2-hydroxymethoxymethyl)guanine] complex have been prepared and characterised by X-ray diffraction and IR data; 1H and 13C NMR have been used to interpret the structural characteristics of the complexes in solution. Compounds 1 and 2 exist as octahedral complexes with four H2O ligands in the basal plane [Ni–OW 2.053(2) and 2.057(7) A] and two axial ACV molecules linked to Ni through N(7) [Ni–N(7) 2.160(2) A]. Two additional ACV molecules are included in the outer sphere of the complex, interacting by means of hydrogen bonds with the co-ordinated ACVs. This reveals the unprecedented recognition of free acyclovir molecules by Ni(or Co)-ACV (1 and 2). The monomeric zinc(II) complex 3 exhibits a distorted-tetrahedral geometry, involving two chlorides, the N(7) of the ACV ligand [Zn–N(7) 2.009(2) A] and a water molecule. The hydrogen bonding of two guanine bases via NH2 and N(3) (unit 1) with N(3) and NH2 (unit 2) represents a novel type of interaction between nucleobases. In the case of the cadmium(II) complex 4 the structure is built by polymeric (CdCl2)n chains which are held together by ACV ligands. The cadmium cation is octahedrically coordinated by four chlorides, the N(7) from an ACV molecule and the hydroxylic oxygen from another ACV molecule, the latter two atoms being placed in cis disposition. On the other hand, the complex [{Hg(ACV)Cl2}x] 5 can be tentatively assigned as a polymer by comparison with analogous guanosine systems and spectroscopic and conductometric data.

29 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The CH/π interaction is a kind of hydrogen bond operating between a soft acid CH and a soft base π-system (double and triple bonds, C6 and C5 aromatic rings, heteroaromatics, convex surfaces of fullerenes and nanotubes) as discussed by the authors.
Abstract: The nature and characteristics of the CH/π interaction are discussed by comparison with other weak molecular forces such as the CH/O and OH/π interaction. The CH/π interaction is a kind of hydrogen bond operating between a soft acid CH and a soft base π-system (double and triple bonds, C6 and C5 aromatic rings, heteroaromatics, convex surfaces of fullerenes and nanotubes). The consequences of CH/π hydrogen bonds in supramolecular chemistry are reviewed on grounds of recent crystallographic findings and database analyses. The topics include intramolecular interactions, crystal packing (organic and organometallic compounds), host/guest complexes (cavity-type inclusion compounds of cyclodextrins and synthetic macrocyclic hosts such as calixarenes, catenanes, rotaxanes and pseudorotaxanes), lattice-inclusion type clathrates (including liquid crystals, porphyrin derivatives, cyclopentadienyl compounds and C60 fullerenes), enantioselective clathrate formation, catalytic enantioface discriminating reactions and solid-state photoreaction. The implications of the CH/π concept for crystal engineering and drug design are evident.

1,262 citations

Journal ArticleDOI
TL;DR: This review describes a multidimensional treatment of molecular recognition phenomena involving aromatic rings in chemical and biological systems that facilitates the development of new advanced materials and supramolecular systems, and should inspire further utilization of interactions with aromatic rings to control the stereochemical outcome of synthetic transformations.
Abstract: This review describes a multidimensional treatment of molecular recognition phenomena involving aromatic rings in chemical and biological systems. It summarizes new results reported since the appearance of an earlier review in 2003 in host-guest chemistry, biological affinity assays and biostructural analysis, data base mining in the Cambridge Structural Database (CSD) and the Protein Data Bank (PDB), and advanced computational studies. Topics addressed are arene-arene, perfluoroarene-arene, S⋅⋅⋅aromatic, cation-π, and anion-π interactions, as well as hydrogen bonding to π systems. The generated knowledge benefits, in particular, structure-based hit-to-lead development and lead optimization both in the pharmaceutical and in the crop protection industry. It equally facilitates the development of new advanced materials and supramolecular systems, and should inspire further utilization of interactions with aromatic rings to control the stereochemical outcome of synthetic transformations.

1,221 citations

Journal ArticleDOI
TL;DR: This critical review covers advances in anion complexation in the year 2010 and highlights the applications to which anion receptors can be applied such as sensing, anion transport, control of molecular motion and gelation.
Abstract: This critical review covers advances in anion complexation in the year 2010. The review covers both organic and inorganic systems and also highlights the applications to which anion receptors can be applied such as sensing, anion transport, control of molecular motion and gelation (179 references).

583 citations