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Julia K. Goodrich

Researcher at Broad Institute

Publications -  51
Citations -  44184

Julia K. Goodrich is an academic researcher from Broad Institute. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 24, co-authored 46 publications receiving 36110 citations. Previous affiliations of Julia K. Goodrich include Cornell University & Boston Children's Hospital.

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An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

TL;DR: A ‘taxonomy to tree’ approach for transferring group names from an existing taxonomy to a tree topology is developed and used to apply the Greengenes, National Center for Biotechnology Information (NCBI) and cyanoDB (Cyanobacteria only) taxonomies to a de novo tree comprising 408 315 sequences.
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Human Genetics Shape the Gut Microbiome

TL;DR: Compared microbiotas across >1,000 fecal samples obtained from the TwinsUK population, many microbial taxa whose abundances were influenced by host genetics were identified.
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Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy

TL;DR: It is indicated that host-microbial interactions that impact host metabolism can occur and may be beneficial in pregnancy and when transferred to germ-free mice, T3 microbiota induced greater adiposity and insulin insensitivity compared to T1.
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Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome

TL;DR: Results support the emerging concept that perturbed host–microbiota interactions resulting in low-grade inflammation can promote adiposity and its associated metabolic effects and suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.