J
Julia K. Goodrich
Researcher at Broad Institute
Publications - 51
Citations - 44184
Julia K. Goodrich is an academic researcher from Broad Institute. The author has contributed to research in topics: Microbiome & Gut flora. The author has an hindex of 24, co-authored 46 publications receiving 36110 citations. Previous affiliations of Julia K. Goodrich include Cornell University & Boston Children's Hospital.
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Journal ArticleDOI
QIIME allows analysis of high-throughput community sequencing data.
J. Gregory Caporaso,Justin Kuczynski,Jesse Stombaugh,Kyle Bittinger,Frederic D. Bushman,Elizabeth K. Costello,Noah Fierer,Antonio Gonzalez Peña,Julia K. Goodrich,Jeffrey I. Gordon,Gavin A. Huttley,Scott T. Kelley,Dan Knights,Jeremy E. Koenig,Ruth E. Ley,Catherine A. Lozupone,Daniel McDonald,Brian D. Muegge,Meg Pirrung,Jens Reeder,Joel Sevinsky,Peter J. Turnbaugh,William A. Walters,Jeremy Widmann,Tanya Yatsunenko,Jesse R. Zaneveld,Rob Knight,Rob Knight +27 more
TL;DR: An overview of the analysis pipeline and links to raw data and processed output from the runs with and without denoising are provided.
Journal ArticleDOI
An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea
Daniel McDonald,Morgan N. Price,Julia K. Goodrich,Julia K. Goodrich,Eric P. Nawrocki,Todd Z. DeSantis,Alexander J. Probst,Alexander J. Probst,Gary L. Andersen,Rob Knight,Rob Knight,Philip Hugenholtz +11 more
TL;DR: A ‘taxonomy to tree’ approach for transferring group names from an existing taxonomy to a tree topology is developed and used to apply the Greengenes, National Center for Biotechnology Information (NCBI) and cyanoDB (Cyanobacteria only) taxonomies to a de novo tree comprising 408 315 sequences.
Journal ArticleDOI
Human Genetics Shape the Gut Microbiome
Julia K. Goodrich,Jillian L. Waters,Angela C. Poole,Jessica L. Sutter,Omry Koren,Ran Blekhman,Michelle Beaumont,Will Van Treuren,Rob Knight,Rob Knight,Jordana T. Bell,Tim D. Spector,Andrew G. Clark,Ruth E. Ley +13 more
TL;DR: Compared microbiotas across >1,000 fecal samples obtained from the TwinsUK population, many microbial taxa whose abundances were influenced by host genetics were identified.
Journal ArticleDOI
Host Remodeling of the Gut Microbiome and Metabolic Changes during Pregnancy
Omry Koren,Julia K. Goodrich,Tyler C. Cullender,Aymé Spor,Kirsi Laitinen,Helene Kling Bäckhed,Antonio Gonzalez,Jeffrey J. Werner,Largus T. Angenent,Rob Knight,Rob Knight,Fredrik Bäckhed,Erika Isolauri,Seppo Salminen,Ruth E. Ley +14 more
TL;DR: It is indicated that host-microbial interactions that impact host metabolism can occur and may be beneficial in pregnancy and when transferred to germ-free mice, T3 microbiota induced greater adiposity and insulin insensitivity compared to T1.
Journal ArticleDOI
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
Benoit Chassaing,Omry Koren,Julia K. Goodrich,Angela C. Poole,Shanthi Srinivasan,Ruth E. Ley,Andrew T. Gewirtz +6 more
TL;DR: Results support the emerging concept that perturbed host–microbiota interactions resulting in low-grade inflammation can promote adiposity and its associated metabolic effects and suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.