J
Julia Salzman
Researcher at Stanford University
Publications - 82
Citations - 8485
Julia Salzman is an academic researcher from Stanford University. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 22, co-authored 61 publications receiving 6685 citations. Previous affiliations of Julia Salzman include Princeton University & Howard Hughes Medical Institute.
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Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types
TL;DR: By deep sequencing of RNA from a variety of normal and malignant human cells, this work suggests that a non-canonical mode of RNA splicing, resulting in a circular RNA isoform, is a general feature of the gene expression program in human cells.
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Cell-type specific features of circular RNA expression.
TL;DR: Using an improved computational approach for circular RNA identification, widespread circular RNA expression is found in Drosophila melanogaster and it is estimated that in humans, circular RNA may account for 1% as many molecules as poly(A) RNA.
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Circular RNAs: analysis, expression and potential functions.
Steven P. Barrett,Julia Salzman +1 more
TL;DR: This Primer outlines the discovery, roles and regulation of circular RNAs, focussing on their potential functions during development and on the regulation of and functional roles played by these molecules.
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Circular RNA Is Expressed across the Eukaryotic Tree of Life
Peter L. Wang,Yun Bao,Muh-Ching Yee,Steven P. Barrett,Gregory J. Hogan,Mari Olsen,José R. Dinneny,Patrick O. Brown,Julia Salzman +8 more
TL;DR: It is reported that circular RNA isoforms are found in diverse species whose most recent common ancestor existed more than one billion years ago: fungi, plants, a plant, and protists, including S. pombe, which may be an ancient, conserved feature of eukaryotic gene expression programs.
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Circular RNA Expression: Its Potential Regulation and Function
TL;DR: Together, these features raise fundamental questions regarding the regulation of circRNA in cis and in trans, and its function, which are enriched in the brain and increase in abundance during fetal development.