J
Julie Audet
Researcher at University of Toronto
Publications - 40
Citations - 4715
Julie Audet is an academic researcher from University of Toronto. The author has contributed to research in topics: Stem cell & Haematopoiesis. The author has an hindex of 19, co-authored 37 publications receiving 3703 citations. Previous affiliations of Julie Audet include Laval University & University of British Columbia.
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Journal ArticleDOI
Analysis of nanoparticle delivery to tumours
Stefan Wilhelm,Anthony J. Tavares,Qin Dai,Seiichi Ohta,Seiichi Ohta,Julie Audet,Harold F. Dvorak,Warren C. W. Chan +7 more
TL;DR: This Perspective explores and explains the fundamental dogma of nanoparticle delivery to tumours and answers two central questions: ‘ how many nanoparticles accumulate in a tumour?’ and ‘how does this number affect the clinical translation of nanomedicines?'
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Current techniques for single-cell lysis
Robert B. Brown,Julie Audet +1 more
TL;DR: T careful selection of the proper lysis technique is essential for gathering accurate data from single cells in capillaries and lab-on-a-chip devices.
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Distinct role of gp130 activation in promoting self-renewal divisions by mitogenically stimulated murine hematopoietic stem cells
TL;DR: Flt3-ligand and Steel factor alone will stimulate >85% of c-kit(+)Sca-1(+)lin(-) adult mouse bone marrow cells to proliferate in single-cell serum-free cultures, but concomitant retention of their stem cell activity requires additional exposure to a ligand that will activate gp130.
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Automated digital microfluidic platform for magnetic-particle-based immunoassays with optimization by design of experiments.
Kihwan Choi,Alphonsus H. C. Ng,Ryan Fobel,David Chang-Yen,Lyle Yarnell,Elroy L. Pearson,Carl M. Oleksak,Andrew T. Fischer,Robert P. Luoma,John M. Robinson,Julie Audet,Aaron R. Wheeler +11 more
TL;DR: It is proposed that this new platform paves the way for a benchtop tool that is useful for implementing immunoassays in near-patient settings, including community hospitals, physicians' offices, and small clinical laboratories.
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High-resolution tracking of cell division suggests similar cell cycle kinetics of hematopoietic stem cells stimulated in vitro and in vivo
Robert A.J. Oostendorp,Julie Audet,Julie Audet,Julie Audet,Connie J. Eaves,Connie J. Eaves,Connie J. Eaves +6 more
TL;DR: Flow cytometric analysis of CFSE(+) cells recovered from the BM of transplanted mice indicated that these cells proliferated slightly faster, and FL, SF, and ligands which activate gp130 are thus efficient stimulators of transplantable stem cell self-renewal divisions in vitro.