J
Julie Jerber
Researcher at Wellcome Trust Sanger Institute
Publications - 3
Citations - 201
Julie Jerber is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Induced pluripotent stem cell & Expression quantitative trait loci. The author has an hindex of 3, co-authored 3 publications receiving 61 citations.
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Journal ArticleDOI
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
Julie Jerber,Daniel D Seaton,Anna S E Cuomo,Natsuhiko Kumasaka,James Haldane,Juliette Steer,Minal Patel,Daniel Pearce,Malin Andersson,Marc Jan Bonder,Ed Mountjoy,Maya Ghoussaini,Madeline A. Lancaster,John C. Marioni,John C. Marioni,John C. Marioni,Florian T. Merkle,Daniel J. Gaffney,Oliver Stegle +18 more
TL;DR: In this article, the authors used an efficient multiplexing strategy to differentiate 215 human induced pluripotent stem cell (iPSC) lines toward a midbrain neural fate, including dopaminergic neurons, and use single-cell RNA sequencing (scRNA-seq) to profile over 1 million cells across three differentiation time points.
Posted ContentDOI
Population-scale single-cell RNA-seq profiling across dopaminergic neuron differentiation
Julie Jerber,Daniel D Seaton,Anna S E Cuomo,Natsuhiko Kumasaka,James Haldane,Juliette Steer,Minal Patel,Daniel Pearce,Malin Andersson,Marc Jan Bonder,Ed Mountjoy,Maya Ghoussaini,Madeline A. Lancaster,John C. Marioni,John C. Marioni,John C. Marioni,Florian T. Merkle,Oliver Stegle,Daniel J. Gaffney +18 more
TL;DR: This study uses an efficient pooling strategy to differentiate 215 iPS cell lines towards a midbrain neural fate, and profiles over 1 million cells sampled across three differentiation timepoints using single cell RNA sequencing.
Journal ArticleDOI
Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis.
Peter Kirwan,Richard G. Kay,Bas Brouwers,Vicente Herranz Pérez,Magdalena Jura,Pierre Larraufie,Julie Jerber,Jason Pembroke,Theresa Bartels,Anne White,Fiona M. Gribble,Frank Reimann,I. Sadaf Farooqi,Stephen O'Rahilly,Florian T. Merkle +14 more
TL;DR: The findings challenge the assumed pre-eminence of α-MSH and suggest that in humans, d-α- MSH and β-MSh are likely to be the predominant physiological products acting on melanocortin receptors.