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Julie M. Legler

Researcher at National Institutes of Health

Publications -  22
Citations -  7897

Julie M. Legler is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Prostate cancer & Prostate-specific antigen. The author has an hindex of 19, co-authored 22 publications receiving 7512 citations. Previous affiliations of Julie M. Legler include Harvard University.

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Development of a comorbidity index using physician claims data.

TL;DR: A comorbidity index that incorporates the diagnostic and procedure data contained in Medicare physician (Part B) claims and demonstrates the utility of a disease-specific index using an alternative method of construction employing study-specific weights.

PHARMACOEPIDEMIOLOGY REPORT Development of a comorbidity index using physician claims data

TL;DR: This article developed a comorbidity index that incorporates the diagnostic and procedure data contained in Medicare physician (Part B) claims, which significantly contributes to models of 2-year noncancer mortality and treatment received in both patient cohorts.
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Overdiagnosis Due to Prostate-Specific Antigen Screening: Lessons From U.S. Prostate Cancer Incidence Trends

TL;DR: The results suggest that the majority of screen-detected cancers diagnosed between 1988 and 1998 would have presented clinically and that only a minority of cases found at autopsy would have been detected by PSA testing.
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Cancer Surveillance Series: Interpreting Trends in Prostate Cancer—Part I: Evidence of the Effects of Screening in Recent Prostate Cancer Incidence, Mortality, and Survival Rates

TL;DR: The decline in the incidence of distant stage disease holds the promise that testing for prostate-specific antigen may lead to a sustained decline in prostate cancer mortality, however, population data are complex, and it is difficult to confidently attribute relatively small changes in mortality to any one cause.
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Health outcomes after prostatectomy or radiotherapy for prostate cancer: results from the Prostate Cancer Outcomes Study.

TL;DR: There are important differences in urinary, bowel, and sexual functions over 2 years after different treatments for clinically localized prostate cancer and these outcome differences reflect treatment delivered to a heterogeneous group of patients in diverse health care settings.