J
Julien Mendlewicz
Researcher at Université libre de Bruxelles
Publications - 535
Citations - 21902
Julien Mendlewicz is an academic researcher from Université libre de Bruxelles. The author has contributed to research in topics: Major depressive disorder & Bipolar disorder. The author has an hindex of 73, co-authored 524 publications receiving 20765 citations. Previous affiliations of Julien Mendlewicz include Max Planck Society & Free University of Brussels.
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Journal ArticleDOI
Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder.
Ricardo Segurado,Sevilla D. Detera-Wadleigh,Douglas F. Levinson,Cathryn M. Lewis,Michael Gill,John I. Nurnberger,Nicholas John Craddock,J. Raymond DePaulo,Miron Baron,Elliot S. Gershon,Jenny Ekholm,Sven Cichon,Gustavo Turecki,Stephan Claes,John R. Kelsoe,Peter R. Schofield,Renee F. Badenhop,Renee F. Badenhop,Jean Morissette,Hilary Coon,Douglas Blackwood,L. Alison McInnes,Tatiana Foroud,Howard J. Edenberg,Theodore Reich,John P. Rice,Alison Goate,Melvin G. McInnis,Francis J. McMahon,Judith A. Badner,Lynn R. Goldin,Phil Bennett,Virginia L. Willour,Peter P. Zandi,Jianjun Liu,Conrad T. Gilliam,S H Juo,Wade H. Berrettini,Takeo Yoshikawa,Leena Peltonen,Leena Peltonen,Jouko Lönnqvist,Markus M. Nöthen,Johannes Schumacher,Christine Windemuth,Marcella Rietschel,Peter Propping,Wolfgang Maier,Martin Alda,Paul Grof,Guy A. Rouleau,Jurgen Del-Favero,Christine Van Broeckhoven,Julien Mendlewicz,Rolf Adolfsson,M. Anne Spence,Hermann Luebbert,L. J. Adams,Jennifer A. Donald,Philip B. Mitchell,Nicholas Barden,Eric Shink,William Byerley,Walter J. Muir,Peter M. Visscher,Stuart MacGregor,Hugh Gurling,Gursharan Kalsi,Andrew McQuillin,Michael Escamilla,Victor I. Reus,Pedro León,Nelson B. Freimer,Henrik Ewald,Torben A Kruse,Ole Mors,Uppala Radhakrishna,Jean-Louis Blouin,Stylianos E. Antonarakis,Nurten A. Akarsu +79 more
TL;DR: The present results for the very narrow model are promising but suggest that more and larger data sets are needed to support linkage, as well as suggest that linkage might be detected in certain populations or subsets of pedigrees.
Journal ArticleDOI
Depression in the community: the first pan-European study DEPRES (Depression Research in European Society)
TL;DR: The results of the DEPRES survey confirm the high prevalence of depression in the community and the burden imposed on the individual sufferer in terms of impaired quality of life and on society in termsof healthcare utilization and lost productivity.
Journal ArticleDOI
Clinical factors associated with treatment resistance in major depressive disorder: results from a European multicenter study.
Daniel Souery,Pierre Oswald,Isabelle Massat,Ursula F. Bailer,Joseph Bollen,Koen Demyttenaere,Siegfried Kasper,Yves Lecrubier,Stuart Montgomery,Alessandro Serretti,Joseph Zohar,Julien Mendlewicz +11 more
TL;DR: The findings provide a set of 11 relevant clinical variables associated with treatment resistance in major depressive disorder that can be explored at the clinical level and show that comorbid anxiety disorder is the most powerful clinical factor associated with TRD.
Journal ArticleDOI
The 24-hour profile of adrenocorticotropin and cortisol in major depressive illness.
Paul Linkowski,Julien Mendlewicz,Raoul Leclercq,Michele Brasseur,Ph.P. Hubain,Jacqueline Golstein,Georges Copinschi,E. Van Cauter +7 more
TL;DR: The results indicate that major depressive illness is associated with disturbances of pituitary-adrenal function and the early timing of the nadir of ACTH-cortisol secretion suggests that disorders of circadian time keeping may characterize major endogenous depression.
Journal ArticleDOI
Treatment resistant depression: methodological overview and operational criteria.
Daniel Souery,Jay D. Amsterdam,C de Montigny,Yves Lecrubier,Stuart Montgomery,Olivier Lipp,Giorgio Racagni,Joseph Zohar,Julien Mendlewicz +8 more
TL;DR: The proposed criteria are intended for therapeutic trials in TRD, combining the evaluation of treatment efficiency and the validation of the concept of TRD itself, including major depression with poor response to two adequate trials of different classes of antidepressants.