J
Julien P. H. Verheyden
Publications - 70
Citations - 2479
Julien P. H. Verheyden is an academic researcher. The author has contributed to research in topics: Guanine & Nucleoside. The author has an hindex of 25, co-authored 70 publications receiving 2434 citations.
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Preparation and Synthetic Utility of Some Organotin Derivatives of nucleosides
Journal ArticleDOI
Anti-herpesvirus activity of the acyclic nucleoside 9-(1,3-dihydroxy-2-propoxymethyl)guanine.
TL;DR: Although the two compounds had many similarities in their behavior in vitro, the important difference was the superior performance of DHPG against herpesvirus-induced encephalitis and vaginitis in vivo.
Journal ArticleDOI
Synthesis and anti-HIV activity of 4'-azido- and 4'-methoxynucleosides.
Hans Maag,Robert M. Rydzewski,Mary Jane McRoberts,D. Crawford-Ruth,Julien P. H. Verheyden,Prisbe Ernest J +5 more
TL;DR: Reaction-mechanism considerations, empirical conformation rules, NMR-based conformational calculations, and NOE experiments suggest that the 4'-azidonucleosides prefer a 3'-endo (N-type) conformation of the furanose moiety.