Author
Julijana Kristl
Bio: Julijana Kristl is an academic researcher from University of Ljubljana. The author has contributed to research in topics: Nanofiber & Electrospinning. The author has an hindex of 46, co-authored 129 publications receiving 6380 citations.
Papers published on a yearly basis
Papers
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TL;DR: This study demonstrates a method by which mAbs can be bound to nanoparticles without detriment to their targeting ability and shows the effectiveness of the new carrier system for targeted delivery of small or large active substances into cells or tissues of interest.
418 citations
TL;DR: The investigation shows that tablet composition and mechanical strength have the greatest influence on the floating properties and drug release of the floating matrix tablets after oral administration.
386 citations
TL;DR: The formulation of ibuprofen as a nanosuspension, either in the form of lyophilized powder or granules, was very successful in enhancing dissolution rate, and the increase in in vitro dissolution rate may favourably affect bioavailability and improve safety for the patient by decreasing gastric irritancy.
370 citations
TL;DR: Delivering RSV by SLN contributes to effectiveness of RSV on decreasing cell proliferation, with potential benefits for prevention of skin cancer.
241 citations
TL;DR: Newly determined trans-RSV solubility and stability at various pH and temperatures, and the importance of such data for the studies of novel trans- RSV-loaded nanofibers are presented.
239 citations
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TL;DR: Relevant issues for the introduction of SLN to the pharmaceutical market, such as status of excipients, toxicity/tolerability aspects and sterilization and long-term stability including industrial large scale production are discussed.
3,260 citations
TL;DR: An overview about the selection of the ingredients, different ways of SLN production and SLN applications, and the in vivo fate of the carrier are presented.
2,786 citations
TL;DR: The fundamental concepts of enhanced permeability and retention effect (EPR) are revisited and the mechanisms proposed to enhance preferential "retention" in the tumor, whether using active targeting of nanoparticles, binding of drugs to their tumoral targets or the presence of tumor associated macrophages are explored.
2,199 citations
TL;DR: The Essay concludes that practitioners theorize, and theorists practice, use these intellectual tools differently because the goals and orientations of theorists and practitioners, and the constraints under which they act, differ.
Abstract: Much has been written about theory and practice in the law, and the tension between practitioners and theorists. Judges do not cite theoretical articles often; they rarely "apply" theories to particular cases. These arguments are not revisited. Instead the Essay explores the working and interaction of theory and practice, practitioners and theorists. The Essay starts with a story about solving a legal issue using our intellectual tools - theory, practice, and their progenies: experience and "gut." Next the Essay elaborates on the nature of theory, practice, experience and "gut." The third part of the Essay discusses theories that are helpful to practitioners and those that are less helpful. The Essay concludes that practitioners theorize, and theorists practice. They use these intellectual tools differently because the goals and orientations of theorists and practitioners, and the constraints under which they act, differ. Theory, practice, experience and "gut" help us think, remember, decide and create. They complement each other like the two sides of the same coin: distinct but inseparable.
2,077 citations
1,837 citations